Conference: Arabidopsis Informatics Workshops, UK and Arlington, VA

智力优势：本提案要求支持两个相关的研讨会，以讨论拟南芥社区对数据库支持的不断发展的需求。目前拟南芥数据库TAIR正处于内容、可持续性以及与其他植物和其他生物数据库资源整合的十字路口。拟南芥和许多其他植物的DNA序列数据、表达分析、蛋白质相互作用数据、表型表征和其他数据的数量不断增加，需要新的视角来确保数据的存储、整理和可用性。一种全新的生物研究方法的基础是对这些大量数据的快速恢复和分析。第一次研讨会将于2010年春季在英国举行，由跨国拟南芥指导委员会组织，BBSRC提供所有现场支持。本提案涵盖美国与会者参加第一次研讨会的旅费。英国研讨会将包括关于拟南芥和其他植物信息学和数据库现状的报告和分组会议。该研讨会将产生一个大纲，并将在由北美拟南芥指导委员会组织的第二次研讨会上提交给信息学专家、植物生物学家和来自合成中心和商业部门的代表，该研讨会将于2010年5月10日至11日在美国华盛顿特区举行。目前提案的大部分内容是请求支持美国研讨会的组织和出席。第二次研讨会将讨论英国会议提出的问题，目的是产生潜在的解决方案。将编写一份载有两个讲习班的分析和建议的最后报告。更广泛的影响：定义生物群落的信息需求以及如何管理这些数据是持续的挑战。研究数据访问的解决方案对整个拟南芥社区以及所有科学领域的研究人员都至关重要。因此，本次研讨会的成果将在植物研究领域和更大的生物科学领域产生广泛的影响。

Intellectual Merit:This proposal requests support for two related workshops to discuss the evolving needs of the Arabidopsis community for database support. The current Arabidopsis database TAIR is at a crossroads concerning content, sustainability, and integration with database resources for other plants and other organisms. The expanding amount of DNA sequence data, expression analysis, protein interaction data, phenotypic characterization and other data for both Arabidopsis and numerous other plants requires new vision to ensure that data are deposited, curated and made available appropriately. An entire new approach to biological research has as its underpinnings the facile recovery and analysis of these vast amounts of data. The first workshop, organized by the Multinational Arabidopsis Steering Committee and with all onsite support provided by the BBSRC, will be held in the UK in Spring 2010. This proposal covers cost for travel of the US participants to this first workshop. The UK workshop will comprise presentations and breakout sessions on the current state of informatics and databases in Arabidopsis and other plants. The workshop will generate an outline that will be presented to informatics experts, plant biologists and representatives from synthesis centers and the commercial sector at a second workshop, organized by the North American Arabidopsis Steering Committee to be held in the US May10-11, 2010 in Washington, DC. The majority of the current proposal is a request for support of the US workshop organization and attendance. This second workshop will discuss the issues raised by the UK meeting with the intent to generate potential solutions. A final report containing analysis and recommendations from both workshops will be produced. Broader Impacts:Defining the informatic needs of the biological community and how to manage these data are ongoing challenges. Working towards solutions for data access is critical to the entire Arabidopsis community, as well as to researchers in all fields of science. Therefore, the outcome of this workshop will have wide-ranging impact in the field of plant research and the larger area of biological sciences.