SHB: Small: InteCog System: ClockReader+ and CogStim Game for Screening and Preventing Cognitive Impairment

与年龄相关的认知障碍，包括阿尔茨海默病，是美国最常见的疾病之一。通过延迟进行预防目前被认为是解决阿尔茨海默病及相关疾病(ADRD)的最佳方法。早期发现是至关重要的，因为对轻度认知障碍(MCI)患者进行筛查可能会延缓其进展并阻止其发展。这项研究调查了技术对有潜在MCI高危因素的老年人和医生(如神经学家或神经心理学家)做出数据驱动临床决策的作用。绘制时钟测试要求患者画一个显示特定时间的时钟，是筛查痴呆症最简单和最常用的工具之一。目前的做法要求医生对每一项纸笔测试进行管理和评估。它需要繁琐的努力，并且在不同的临床医生之间容易出错和评分不一致。为了解决这些困难，该研究小组之前的工作已经产生了一个基于计算机的版本的钟表绘制测试，它记录了患者在平板电脑上的徒手绘制，然后分析绘制的图形以寻找认知传授的证据。目前的项目是扩展基于计算机的系统以获取与钟表绘制测试相关的更多数据。这些数据包括绘制和暂停阶段的时间，以及在绘制期间施加的压力。这些数据可以用于在临床医生可以选择的几种不同评分标准下对图纸进行评估。通过数据分析和焦点小组讨论，正在评估新功能的临床应用，以期进一步改进。

Age-related cognitive impairments, including Alzheimer's disease, are among the most common diseases in the United States. Prevention through delay is currently considered the best way to tackle Alzheimer's disease and related disorders (ADRD). Early detection is crucial, as screening individuals with Mild Cognitive Impairment (MCI) may delay its progression and prevent it from developing. This research investigates the role of technologies for senior citizens with potential MCI at-risk factors and for medical practitioners, such as neurologists or neuropsychologists, to make data-driven clinical decisions.The Clock Drawing Test, in which the patient is asked to draw a clock showing a certain time, is one of the easiest and most frequently used instruments for dementia screening. Current practice requires medical practitioners to administer and assess each individual paper-and-pencil test. It requires tedious effort and is prone to errors and inconsistent scoring among different clinicians. To address these difficulties, previous work by this research group has resulted in a computer-based version of the Clock Drawing Test that records a patient's freehand drawing on a tablet computer, then analyzes the drawing for evidence of cognitive imparment.The current project is extending the computer-based system to acquire additional data associated with the Clock Drawing Test. This data includes timing of drawing and pausing phases, and pressure applied during drawing. The data can be used in evaluating drawings under several different scoring critera that can be chosen by the clinician. Through analysis of data and focus group discussions, the clinical utility of the new features are being evaluated with a goal of further improvement.