MRI: Acquisition of a LSM710 Laser Scanning Confocal Microscope to Enhance Plant Research and Training at the University of North Texas

该核磁共振奖资助购买LSM710激光扫描共聚焦显微镜，通过提供细胞和亚细胞水平的分子和生化研究所需的成像能力，支持北得克萨斯大学在植物信号方面的研究和培训。此外，共焦显微镜将加强发育生理学、生态毒理学、神经生物学和微生物学的研究和培训。LSM710将配备34个通道的光谱探测器，有助于研究基因的现场表达模式、细胞内蛋白质定位和蛋白质-蛋白质相互作用、钙离子、活性氧物种和糖通量的变化以及大分子动力学。广泛影响：LSM710将通过为他们提供研究和开发应用成像技术的培训，使本科生、研究生和博士后受益。共焦显微镜还将提供机会，通过麦克奈尔计划、德克萨斯州北部教师计划、德克萨斯数学与科学学院、荣誉学院、美国国家科学基金会S资助(#0807128)培养优秀本科生(Focus)奖学金计划和北德克萨斯大学霍华德·休斯医学院本科生科学教育计划，鼓励和扩大未被充分代表的少数族裔、高中生和未来的中学教师参与和培训生命科学。LSM710将支持这些学生的研究。该工具将通过支持植物信号机制的发现、功能和应用的研究，对环境和社会产生积极影响，这将增强可持续农业、工业和可再生自然资源。

This MRI award funds the acquisition of a LSM710 laser scanning confocal microscope tosupport research and training in plant signaling at the University of North Texas by providingimaging capabilities that are required for molecular and biochemical studies at the cellular andsub-cellular levels. In addition, the confocal microscope will enhance research and training indevelopmental physiology, eco-toxicology, neurobiology and microbiology. The LSM710 willcome equipped with a 34-channel spectral detector that will facilitate studying the in situexpression pattern of genes, intracellular protein localization and protein-protein interactions,changes in Ca2+, reactive oxygen species and sugar fluxes, and macromolecular dynamics.Broader Impacts: The LSM710 will benefit undergraduate and graduate students and post-docsby providing them training in the application of imaging technology for research anddevelopment. The confocal microscope will also provide opportunities to encourage andbroaden the participation and training in the Life Sciences of underrepresented minorities, highschool-aged students and future secondary teachers through the McNair program, the TeachNorth Texas program, the Texas Academy of Mathematics and Science, the Honors College, theNSF S-STEM supported (#0807128) Fostering Outstanding Cohorts in Undergraduate Science(FOCUS) Scholarships program, and the Howard Hughes Medical Institute UndergraduateScience Education program at the University of North Texas. The LSM710 will supportresearch by these students. The instrument will positively impact the environment and societyby supporting research on the discovery, function and application of signaling mechanisms inplants, which will augment sustainable agriculture, industry and renewable natural resources.