Instrument Development: Ultra-Sensitive, Single-Pass Electron Paramagnetic Resonance Spectrometers

该奖项由化学学部化学测量与成像项目资助，克莱姆森大学王平山教授和他的研究生将开发一种超灵敏的单通电子顺磁共振（EPR）光谱仪，用于研究液相中的顺磁样品。该仪器将利用单通EPR传感器，利用设备内的干扰过程。该仪器灵敏度高，速度快，比目前的x波段光谱仪好一个数量级。EPR光谱仪是化学研究中必不可少的强大分析工具。它们可用于检测样品材料中电子自旋的存在。除了揭示未配对电子自旋的存在（如在反应性化学物质的情况下），EPR光谱揭示了化学环境的独特细节，这有助于理解“自旋标签”周围的分子环境。这个研究项目的一个关键组成部分是它的教育目标，它涉及许多从事科学研究的学生（从研究生院到高中）。通过这项研究开发的仪器设计将通过克莱姆森大学的一个网站以及康奈尔大学的国家生物医学研究中心（ACERT）广泛传播。

In this award, funded by the Chemical Measurement and Imaging Program of the Division of Chemistry, Professor Pingshan Wang of Clemson University and his graduate students will be supported to develop an ultra-sensitive, single-pass electron paramagnetic resonance (EPR) spectrometer for the study of paramagnetic samples in the liquid phase. The instrument will utilize single-pass EPR sensors that exploit interference processes within the devices. The proposed instrument will be sensitive and fast - an order of magnitude better than current X-band spectrometers.EPR spectrometers are essential and powerful analytical tools for chemical studies. They may be used to detect the presence of electron spin in sample materials. Besides revealing the presence of unpaired electron spin (as in the case of reactive chemical species) the EPR spectra reveal unique details about the chemical environment, which help in understanding the molecular milieu around "spin labels". A key component of this research program is its educational objectives, which involve a number of students (from graduate school down to high school) who are engaged in scientific research. The instrument design that is developed through this research will be disseminated broadly through a website at Clemson University, as well as through The National Biomedical Research Center for AdvanCed ESR Technology (ACERT) at Cornell University.