Genomic Approaches to Understanding Cytokinin Signaling and Function in Rice

Pi：Joseph Kieber(北卡罗来纳大学教堂山分校)Copis：G.Eric Schaller(达特茅斯学院)和Ann Loraine(北卡罗来纳大学夏洛特分校)细胞分裂素是调节许多农业重要性状的植物激素，包括控制籽粒大小和产量。在这个项目中，将使用基因组方法来揭示细胞分裂素如何调控水稻的生长和发育，并以这种植物为模型来了解所有谷物的籽粒大小和产量的调节。将使用计算方法来询问和整合由这些研究产生的数据集。预计这些研究将阐明细胞分裂素在穗发育中的作用，并将提供关于细胞分裂素如何调控重要农业作物籽粒发育的具体信息。由于谷物之间基因序列的保守性，从水稻研究中获得的信息可以应用于其他农业上重要的物种，如玉米、小麦、大麦、黑麦和高粱。该项目将通过为本科生、研究生和博士后研究人员提供培训来加强研究和教育的基础设施。计算研讨会将扩大研究界利用基因组学资源的能力。此外，通过与蒙特郡科学博物馆(http://montshire.org/)，)等当地团体建立伙伴关系，将创建和维持旨在促进K-12年级科学教育的方案。数据将通过一个公共数据库(RiceCytokinin.org)以及长期储存库，如国家生物信息局短读档案(http://www.ncbi.nlm.nih.gov/sra/)和基因表达总览(http://www.ncbi.nlm.nih.gov/geo/).))提供在这个项目中产生的种质将根据要求和通过美国农业部遗传储备-水稻(GSOR)收藏(http://www.ars.usda.gov/Main/site_main.htm?docid=18992&amp；page=1).获得

PI: Joseph Kieber (University of North Carolina - Chapel Hill)CoPIs: G. Eric Schaller (Dartmouth College) and Ann Loraine (University of North Carolina - Charlotte)Cytokinins are plant hormones that regulate many traits of agricultural importance, including the control of grain size and yield. In this project, genomic approaches will be used to uncover how cytokinin regulates growth and development in rice, using this plant species as a model to understand the regulation of grain size and yield in all cereals. Computational approaches will be used to interrogate and integrate the datasets generated by these studies. It is expected that these studies will illuminate the role of cytokinins in panicle development, and will provide specific information on how cytokinins regulate grain development in an agriculturally important crop. Because of conservation of gene sequence among cereals, information obtained from the study of rice may be applied to other agriculturally important species such as maize, wheat, barley, rye, and sorghum. This project will enhance the infrastructure of research and education by providing training for undergraduate students, graduate students, and post-doctoral researchers. A computation workshop will broaden the ability of the research community to use genomics resources. In addition, through partnerships with local groups including the Montshire Museum of Science (http://montshire.org/), programs aimed at fostering science education in grades K-12 will be created and maintained. Data will be made available through a public database (RiceCytokinin.org) as well as through long-term repositories such as the NCBI Short Read Archive (http://www.ncbi.nlm.nih.gov/sra/) and the Gene Expression Omnibus (http://www.ncbi.nlm.nih.gov/geo/). Germplasm generated in this project will be available upon request and through the USDA Genetic Stocks - Oryza (GSOR) Collection (http://www.ars.usda.gov/Main/site_main.htm?docid=18992&page=1).