Single Neuron Resolution of Flow Sensing in the Zebrafish Lateral line during development

听觉振动的神经处理在听觉和交流中起着至关重要的作用。这个过程开始于毛细胞将机械刺激转化为神经信号，并随着信号被传输到大脑进行处理而继续。这个项目使用生理学技术来了解与毛细胞相关的神经元之间的功能关系。我们的目标是在一个简单的系统中提供对这些神经元的理解，以便更好地理解它们在更复杂的脊椎动物毛细胞系统中的作用。这项工作的更广泛的影响是促进对正常毛细胞系统功能的理解，这对于更好地理解健康和疾病期间的听觉神经处理的持续进展至关重要。 预计这项工作将有许多应用，从诊断听力障碍到启发机器人传感器设计。 这项工作的更广泛影响还将包括在佛罗里达东北部培训本科生、研究生和博士后助理，该地区历史上一直受到科学素养不足的困扰，并为这些人的独立科学生涯做好准备。

The neural processing of auditory vibrations plays a crucial role in hearing and communication. This process starts when hair cells transform a mechanical stimulus into a neural signal, and continues as the signal is transmitted into the brain for processing. This project uses physiological techniques to understand the functional relationships between neurons associated with hair cells. The goal is to provide an understanding of these neurons in a simple system in order to better understand their role in more complex vertebrate hair cell systems. The broader impact of this work is to advance the understanding of how normal hair cell systems function is essential for continued progress towards of better understanding of auditory neural processing during health and disease. It is anticipated that there will be many applications of this work, from diagnosing hearing disorders to inspiring robotic sensor design. The broader impact of this work will also include training of undergraduates, graduate students and post doctoral associates in Northeast Florida, a region which historically has been plagued with inadequate scientific literacy, and prepare these individuals for independent scientific careers.