Collaborative Research: Enhanced Raman and Rayleigh scattering in an ultrahigh-Q microresonator for detection, identification and measurement of nanoparticles

1264997/1264750 Yang/Liu PI建议开发一类新的纳米颗粒传感器，该传感器基于硅晶片上的质量因子（Q）光学微谐振器，不仅可以实现超灵敏检测，还可以以单颗粒分辨率对空气和液体环境中的纳米颗粒和分子进行分子特异性识别和测量。这种新技术的优点在于增强了拉曼和瑞利散射，并将它们集成到超高Q回音壁模式（WGM）微谐振器中，从而实现多功能传感器。一方面，谐振器中的瑞利散射导致自参考模式分裂，其可用于检测和测量纳米颗粒（例如，尺寸）小至几纳米。另一方面，拉曼散射在超高Q微谐振器中被大大增强了几个数量级，通过识别分子振动的光谱指纹来识别分子/颗粒。通过集成模式分裂和微谐振器增强拉曼光谱，他们可以实现一个多功能的传感单元，能够超灵敏的实时，原位检测，识别和测量单个纳米粒子。

1264997/1264750Yang/LiuThe PIs propose to develop a new class of nanoparticle sensors based on ultrahigh quality factor (Q) optical micro-resonators on a silicon wafer to achieve not only ultra-sensitive detection but also molecule-specific identification and measurement of nanoparticles and molecules in air and in liquid environments at single particle resolution. The merit of this new technique lies in enhancing Raman and Rayleigh scattering and integrating them in an ultrahigh-Q Whispering Gallery mode (WGM) micro resonator to achieve multi-function sensors. On one hand, Rayleigh scattering in resonators leads to self-referencing mode-splitting, which can be utilized to detect and measure nanoparticles (e.g., size) down to several nm in size. On the other hand, Raman scattering, which is greatly enhanced by several orders of magnitude in an ultrahigh-Q microresonator, provides identification of molecules/particles through recognition of their spectral fingerprints of molecular vibrations. By integrating mode-splitting and microresonator-enhanced Raman spectroscopy, they can achieve a multifunction sensing unit capable of ultra-sensitive real-time, in-situ detection, identification and measurement of single nanoparticles.