Investigating the Ability of Honey to Inhibit Bacterial Biofilms Found in Chronic Wounds
Investigating the Ability of Honey to Inhibit Bacterial Biofilms Found in Chronic Wounds
批准号:
LP0990949
负责人:
Prof Elizabeth Harry
金额:
$22.11万
依托单位国家:
澳大利亚
项目类别:
Linkage Projects
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-07-15 至 2013-12-31
中文摘要
在澳大利亚,慢性(不愈合)伤口是一个严重的健康问题。四分之一被收容的老年人患有压疮。治疗这些伤口的困难在于,大多数伤口含有被称为生物膜的细菌群落,这些细菌不会被传统的抗生素杀死。来自澳大利亚和新西兰的特殊蜂蜜对慢性伤口治疗有效,可以消除这些生物膜。该项目将确定蜂蜜中起这种作用的成分,并确定它们是如何起作用的,以提供更有效的慢性伤口治疗。它将减少这些伤口在澳大利亚的流行率以及相关的个人创伤和健康费用。
英文摘要
Chronic (non-healing) wounds are a serious health problem in Australia. One quarter of our institutionalized aged population have pressure ulcers. The difficulty in treating these wounds is that most contain communities of bacteria, called biofilms, that are not killed by conventional antibiotics. Special honeys from Australia and NZ that are effective in chronic wound treatment can eradicate these biofilms. This project will identify the components in honey that do this and determine how they do it, to provide a more effective chronic wound treatment. It will decrease the prevalence of these wounds in Australia and the associated personal trauma and health costs.
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