RUI: Harnessing the redox chemistry of silver: fundamental studies of oxidation chemistry at dinuclear silver catalysts

在国家科学基金会化学部化学催化计划的支持下，巴纳德学院的迈克尔·坎贝尔教授正在探索新型银基催化剂的途径。催化剂加速了化学反应，通常有助于产生特定的、所需的产品。银基催化剂的潜力在很大程度上被忽视了，因为人们对银在关键催化过程所需步骤中的行为知之甚少。为了实现这些目标，坎贝尔教授正在设计新的结构，以诱导银基催化剂的新行为。在某些情况下，多个银离子似乎在化学反应中合作，但产品太脆弱，没有实用价值。通过系统地改变银化合物的结构，可以生产出新一代坚固耐用的催化剂。该补助金还支持对本科生进行科学职业培训，特别强调培养实验室和科学交流方面的技能。特别强调增加妇女和其他代表性不足的群体对科学研究的参与。这笔赠款还支持巴纳德学院更广泛的学生社区参与的科学素养活动。在国家科学基金会化学部化学催化计划的支持下，巴纳德学院的迈克尔·坎贝尔教授正在探索开发新型银基催化剂的途径。尽管与其他后过渡金属相比，银的丰度相对较高，成本较低，但银对均相氧化还原的催化作用还不够发达。这从根本上是由于缺乏控制反应性的化学设计原则。到目前为止，与催化有关的氧化银配合物的数据还很少。坎贝尔教授正在系统地探索双核银配合物的氧化还原化学，重点是银-银相互作用在促进氧化还原过程中的作用。这些研究的结果被用来为从碳氢化合物底物中提供有价值的产品的硝烯转移和其他基团转移反应的催化剂设计提供参考。通过专注于银的氧化还原催化，这项研究最终旨在开发综合有用的反应性，而不是可以取代更常用的稀有金属催化剂，如Rh和Ir。巴纳德学院的坎贝尔团队为未来的科学职业培训本科生。作为一所女性文理学院，巴纳德学院在促进女性和其他代表性不足的群体参与科学方面尤为有效。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

With support from the Chemical Catalysis Program in the Division of Chemistry of the National Science Foundation, Professor Michael Campbell at Barnard College is exploring routes to new kinds of silver-based catalysts. Catalysts speed up chemical reactions and often contribute to producing specific, desired products. The potential of silver-based catalysts has been largely overlooked because little is known about how silver behaves during the steps required for key catalytic processes. In order to accomplish these goals, Professor Campbell is designing new structures that will induce novel behavior of silver-based catalysts. In some cases, multiple silver ions appear to cooperate in chemical reactions, but the products are too fragile to be of practical value. By systematically changing in the structure of the silver compounds, a new generation of rugged, useful catalysts may be produced. The grant also supports the training of undergraduate students for careers in science, with specific emphasis on developing skills in the laboratory and in scientific communication. A particular emphasis is placed on increasing the participation of women and other underrepresented groups in scientific research. The grant is also supporting a science literacy campaign involving the broader community of students at Barnard College.With support from the Chemical Catalysis Program in the Division of Chemistry of the National Science Foundation, Professor Michael Campbell at Barnard College is exploring routes to new kinds of silver-based catalysts. Despite silver’s relatively high abundance and lower cost compared to other late transition metals, homogeneous redox catalysis with silver is underdeveloped. This is fundamentally due to a lack of chemical design principles for controlling reactivity. To date there has been little data on oxidized silver complexes that are relevant to catalysis. Professor Campbell is systematically exploring the redox chemistry of dinuclear silver complexes, with a focus on the role of silver–silver interactions in facilitating redox processes. The results of these studies are used to inform catalyst design for nitrene transfer and other group transfer reactions that furnish valuable products from hydrocarbon substrates. By focusing on redox catalysis with silver, this research ultimately aims to develop synthetically useful reactivity than can supplant more commonly used rare-metal catalysts such as rhodium and iridium. The Campbell group at Barnard College trains undergraduate students for future careers in science. As a liberal arts college for women, Barnard is particularly effective in promoting the participation of women and other underrepresented groups in science.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.