MRI: Acquisition of an X-band Continuous-wave Electron Paramagnetic Resonance (EPR) Spectrometer

该奖项由主要研究仪器和化学研究仪器计划支持。加州大学圣地亚哥分校正在购买一台X波段连续波电子顺磁共振（CW-EPR）光谱仪，以支持约书亚菲格罗亚教授和同事加利亚·德贝卢奇纳。一般来说，EPR光谱仪产生分子和固态材料的几何和电子结构的详细信息。它还用于获得有关自由基（短寿命，高反应性物种）的生命周期的信息，这些自由基参与有价值的生物学意义的化学转化。此次收购加强了这个西班牙裔服务机构以及该地区的研究基础设施。该工具通过利用这一现代技术让不同群体的学生参与研究和研究培训，扩大了参与。它还提供培训机会，许多本科生和研究生，以及博士后研究员在这个机构以及几个邻近的机构，如圣地亚哥州立大学和圣地亚哥大学。授予EPR光谱仪的目的是加强各级的研究和教育。仪器的获取影响了表征配位不饱和过渡金属中心的研究。该仪器用于研究开发新的方法来研究细胞中生物大分子的结构和固氮酶的催化机制。此外，EPR提供了进一步探索顺磁性物质在天然和合成黑色素聚合物中的作用以及稳定的含自由基物质的产生及其对小分子的反应性的信息。EPR光谱仪还用于为电子转移反应机制的研究提供信息。 该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This award is supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs. The University of California-San Diego is acquiring an X-band continuous-wave electron paramagnetic resonance (CW-EPR) spectrometer to support Professor Joshua Figueroa and colleague, Galia Debelouchina. In general, an EPR spectrometer yields detailed information on the geometric and electronic structure of molecular and solid-state materials. It is also used to obtain information about the lifetimes of free radicals (short-lived, highly reactive species) involved in valuable chemical transformations of biological interest. The acquisition strengthens the research infrastructure at this Hispanic-Serving Institution as well as in the region. The instrument broadens participation by involving diverse groups of students in research and research training using this modern technique. It also provides training opportunities to many undergraduate and graduate students as well as postdoctoral fellows at this institution as well as several neighboring institutions such as San Diego State University and the University of San Diego. The award of the EPR spectrometer is aimed at enhancing research and education at all levels. The instrument acquisition impacts studies characterizing coordinatively-unsaturated transition metal centers. The instrumentation is used for research on the development of new methodologies to study the structure of biological macromolecules in cells and the catalytic mechanism of nitrogenase. In addition, the EPR provides information to further explore the role of paramagnetic species in natural and synthetic melanin polymers and the generation of stable radical-containing species and their reactivity towards small molecules. The EPR spectrometer is also used to inform studies of the mechanism of electron-transfer reactions. It is utilized in designing transition-metal doped metal oxide materials with precisely tunable electronic and spin-qubit array properties.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.