MRI: Acquisition of a Single Crystal X-ray Diffractometer for Research and Teaching at Missouri State University

该奖项授予密苏里州立大学斯普林菲尔德分校，由主要研究仪器和化学研究仪器项目提供支持，以改进Tiglet Besara博士及其同事Nikolay Gerasimchuk， Gary Michelfelder， Fei Wang和Natasha DeVore的研究。该机构正在获得单晶衍射仪（SCXRD）。一般来说，x射线衍射仪可以精确测量分子的完整三维结构，包括键距和角度，并提供有关分子相对于邻近分子的空间排列的准确信息。这里描述的研究影响许多领域，包括有机和无机化学，材料化学，地质和生物化学。该仪器是我校化学和生物化学专业本科生以及物理、天文、材料科学、地理、地质和规划等系的教学、研究和研究训练的重要组成部分。该仪器为分布在各个系的各种课程的学生提供了直接的研究经验。该机构是材料表征的中心，并为附近的机构提供免费的晶体学服务，如密苏里大学堪萨斯城分校、密苏里科技大学、阿肯色大学和中阿肯色大学。颁发x射线衍射仪的目的是为了加强各级的研究和教育。通过开发解决能源生产的新材料，改善商品和工业化学品合成的新催化剂，该仪器所实现的科学提供了相关的社会效益。该仪器还用于研究功能和量子材料的生长，以及探索和开发用于能源相关应用的金属间材料。此外，它有利于血红素孤儿细胞色素P450和过氧化物酶蛋白的结构生物学研究，以及合成的肟基配体及其金属配合物的表征，以实现可能的生物医学应用。衍射仪还用于表征矿物和火山物质，以及碳氢化合物中的卤素和氢键，以操纵芳炔-乙烯结构。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This award to Missouri State University at Springfield is supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs to improve research by Dr. Tiglet Besara and colleagues Nikolay Gerasimchuk, Gary Michelfelder, Fei Wang and Natasha DeVore. The institution is acquiring a single crystal diffractometer difffractometer (SCXRD). In general, an X-ray diffractometer allows accurate and precise measurements of the full three-dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules. The studies described here impact many areas, including organic and inorganic chemistry, materials chemistry, geology and biochemistry. This instrument is an integral part of teaching as well as research and research training of undergraduate students in chemistry and biochemistry at this institution as well other departments such as Physics, Astronomy, Materials Science, Geography, Geology and Planning. The instrumentation provides direct research experience for students in a variety of courses distributed in various departments. The institution serves as a hub for materials characterization and provides crystallography services free of charge to nearby institutions such as University of Missouri-Kansas City, Missouri University of Science and Technology, University of Arkansas and the University of Central Arkansas.The award of the X-ray diffractometer is aimed at enhancing research and education at all levels. The science enabled by this instrument provides relevant societal benefits through the development of new materials to address energy production, new catalysts to improve the synthesis of commodity and industrial chemicals. The instrumentation is also used for studying the growth of functional and quantum materials and exploring and developing intermetallic materials for energy related applications. In addition, it benefits structural biology studies of heme orphan cytochrome P450 and peroxidase proteins and the characterization of synthesized oxime-based ligands and their metal complexes for possible biomedical applications. The diffractometer is also used to characterize minerals and volcanic materials, and halogen and hydrogen bonding in carbon-hydrogen compounds to manipulate arylene ethynylene structures.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.