Social relationships: key to gut microbiome composition in wild redfronted lemurs?

社会和生态因素是构成个体适应性的主要因素。虽然生态因素，如粮食供应和病原体，基本上塑造个人的条件，社会关系调解获得食物和病原体的传播。此外，社会关系介导生理应激反应并塑造肠道微生物组的组成，而肠道微生物组的组成又受到饮食、病原体和生理应激的影响。由于所有这些因素都相互影响，社会关系似乎是通过多种途径塑造肠道微生物组组成的关键。脊椎动物的肠道微生物群由影响免疫系统的微生物物种组成，因此影响宿主的健康和最终适应性。尽管肠道微生物群对个人健康的重要性，但塑造肠道微生物群落的因素之间的相互关系尚未得到很好的理解。在对野生宿主红额狐猴的纵向研究中，将这些方面，饮食，生理压力，胃肠道寄生虫和身体状况的丰度与肠道微生物组组成以及这些方面如何通过社会关系介导联系起来，将有助于我们理解肠道微生物群组成动态对健康指标的相互关系。

Social and ecological factors mainly constitute individual fitness. Whereas ecological factors, e.g. food availability and pathogens, basically shape individuals condition, social relationships mediate access to food and transmission of pathogens. Moreover, social relationships mediate the physiological stress response and shape the composition of the gut microbiome, which in turn is influenced by diet, pathogens and physiological stress. Since all these factors impact on each other, social relationships appear to be key via multiple pathways in shaping the gut microbiome composition. The gut microbiota in vertebrates consists of microbial species that influence the immune system and, hence, health and ultimately fitness of their hosts. Despite the importance of the gut microbiota for individuals health, the interrelationships of factors shaping the gut microbial community is not yet well understood. Linking these aspects, diet, physiological stress, abundance of gastrointestinal parasites and body condition, with the gut microbiome composition and how these aspects are mediated by social relationships, in a longitudinal study on wild hosts, the redfronted lemurs, will contribute to our understanding on the interrelationship of the gut microbiota compositional dynamics on indicators of health.