Structural Determinants of an Intracellular Calcium Store.

了解肌肉和心脏中钙信号传导中关键蛋白质之间的分子相互作用将允许钙信号传导用作各种目的的平台。这些措施包括减少衰老和遗传或药物诱导的疾病中钙信号和肌肉性能变化的衰弱效应。该项目将有利于澳大利亚的生物技术，因为它将有助于设计新的化合物，用于治疗动物和人类的肌肉疾病，改善肉类质量和用作杀虫剂。该项目将通过我们的商业合作伙伴Biotron促进基础科学的研究生和本科生培训，并接触生物技术。

Understanding the molecular interactions between key proteins in calcium signalling in muscle and the heart will allow calcium signalling to be used as a platform for a variety of purposes. These include reducing the debilitating effects of changes in calcium signalling and muscle performance in aging and in genetically- or drug-induced disorders. The project will have benefits for Australian biotechnology since it will facilitate the design of novel compounds for treating muscle disorders in animals and humans, for improving meat quality and for use as insecticides. The project will facilitate graduate and undergraduate training in basic science with exposure to biotechnology, through our commercial partner Biotron.