ANTIOXIDATION ACTIVITIES OF WOOD EXTRACTIVES,DIARYLHEPANOIDS FROM BETULACEAE,AND HIGHER UTILIZATION OF THE FUNCTION.

为了开发一种有效利用树木资源的方法，对桦木中的二芳基七烷类等80余种木材提取物进行了测试和评价，以期获得新的食品和医药抗氧化剂。该评价基于两个测试结果，即亚油酸甲酯过氧化产物的数值和光密度对1,1-二苯基-2-苦酰肼自由基清除的变化值。进一步讨论了木材提取物的抗氧化活性与结构的相关性。通过试验，发现了许多具有高抗氧化活性的提取物，并将其与二芳基七烷类化合物如三脱氧山五苷等一起列为有效的天然抗氧化剂；氧白藜芦醇和白藜芦醇的stitilbens， robinetin，杨梅素和槲皮素的黄酮类化合物，和双-（对羟基苯基）-1,3-丁二烯的diylbutyoids。此外，从抗氧化活性与萃取物结构的相关性分析中发现，具有较高抗氧化活性的萃取物具有复数芳羟基（邻羟基）、碳双键与芳环共轭（上述二苯乙烯和丁二烯）和/或C-C直接连接的芳环（上述三脱氧山五苷）。

In order to develop an affective utilization method of tree resouces, about 80 wood extractives such as diarylheptanoids of Ostrya japonica wood (Betulaceae) were tested and evaluated to obtain new antioxidants for food and medicine industries. The evaluation was based on two test results, numeric values on peroxidation products of methyl linolate and change values of optical densities on radical-scavenging for 1,1-diphenyl-2-picrylhydrazil radical. Further, the correlation of antioxidation activities and structure of wood extractives was discussed.Based on tests, together with such diarylheptanoids as trideoxyasadanin, many extractives with high antioxidation activities were found out and valued as effective natural antioxidants ; oxyresveratol and resveratrol of stitilbens, robinetin, myricetin and quercetin of flavonoids, and bis- (p-hydroxyphenyl) -1,3-butadiene of diarylbutanoids.Also, from the discussion on the correlation of antioxidation activities and structure of extractives, it was revealed that the extractives with high antioxidation activities possesed plural aromatic hydroxyl groups (vicinal hydroxyl groups) , carbon double bonds conjugating with aromatic rings (in the above stiibene and butadiene) and/or C-C directly connected aromatic rings (in the above trideoxyasadanin).