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Cochlear blood flow in sudden deafness

Cochlear blood flow in sudden deafness
突发性耳聋的耳蜗血流
批准号:
05671424
负责人:
NAKASHIMA Tsutomu
金额:
$1.02万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (C)
财政年份:
1993
资助国家:
日本
项目状态:
已结题
起止时间:
1993 至 1994

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中文摘要
翻译
耳蜗血流障碍可能是突发性耳聋的病理生理学因素之一。本文对9例疑有外淋巴瘘的突发性聋患者进行了耳蜗血流测定。在探索性鼓膜切开术中,将激光多普勒探头的尖端连接到圆窗龛前部附近的岬上。增加了激发光纤和接收光纤之间的距离,以提高最大深度灵敏度。在所有9名患者中,观察到对应于ECG的激光输出的平行移动。我们试图测量二氧化碳对耳蜗血流的影响,如吸入卡波琴和呼吸停止。然而,在大多数情况下,这些程序没有观察到耳蜗血流的显着变化。
英文摘要
Impairment of cochlear blood flow may be one of the factors implicated in the pathophysiology of sudden deafness. Cochlear blood flow in sudden deafness was measured in nine patients who were suspected of having perilymphatic fistulas. During exploratory tympanotomy, the tip of a laser-Doppler probe was attached to the promontory near the anterior portion of the round window niche. The distance between the exciting and receiving optic fibers was increased to elevate the maximum depth sensitivity. In all nine patients, pulsatory movement of the laser output that corresponded to ECG was observed. We attempted to measure effects of carbon dioxide on cochlear blood flow, such as inhalation of carbogen and cessation of respiration. In almost cases, however, no significant change of cochlear blood flow was observed by these procedures.
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Nakashima T,Yanagita N: "Outcome of sudden deafness with and without vertigo." Laryngoscope. 103. 1145-1149 (1993)
Nakashima T、Yanagita N:“伴有或不伴有眩晕的突发性耳聋的结果。”
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Nakashima T,Yanagita N et al.: "Comparative study on sudden deafness by two nationwide epidemiological surveys in Japan" Acta Otolaryngol (Stockh). Suppl 514. 14-16 (1994)
Nakashima T、Yanagita N 等:“日本两次全国流行病学调查对突发性耳聋的比较研究”Acta Otolaryngol (Stockh)。
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共 16 条
    Disruption of the blood-labyrinthine barrier and related genes in sudden sensorineural hearing loss
    • 批准号:
      21390460
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $9.07万
    • 财政年份:
      2009
    • 负责人:
      NAKASHIMA Tsutomu
    • 依托单位:
    Endolymphatic and perilymphatic imaging and investigation of inner-ear diseases
    • 批准号:
      19591964
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.33万
    • 财政年份:
      2007
    • 负责人:
      NAKASHIMA Tsutomu
    • 依托单位:
    Evaluation of inner ear blood flow with laser speckle flowgraphy
    • 批准号:
      15390515
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $7.87万
    • 财政年份:
      2003
    • 负责人:
      NAKASHIMA Tsutomu
    • 依托单位:
    Topical therapy for the treatment of inner ear deafness, tinnitus and vertigo
    • 批准号:
      11470355
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $6.27万
    • 财政年份:
      1999
    • 负责人:
      NAKASHIMA Tsutomu
    • 依托单位:
    海外基金