A study of Artificial Implantation in Periodontal Osseous Defects

1. 本研究的目的是研究牙周组织对羟基磷灰石陶瓷（Periograf）的组织学反应。> >)植入大鼠垂直骨缺损。结果10 d后，磷灰石表面开始形成骨基质。第40天，在磷灰石周围新形成的骨组织表现为成骨细胞分化，随后形成胶原纤维和类骨细胞，并形成许多小而圆的骨晶体沉积。75名患者参加了一项临床研究，比较了两种植入术对牙周骨缺损的反应。在积极的维护计划下，只进行陶瓷或清创，随访6个月。结果如下：实验组术后6个月牙龈退缩、附着度增加、牙袋深度减少和x线片骨充填的平均值分别为1.8mm、2.0mm、3.7mm和62.2%。(2)对照组牙龈退缩、附着深度增加、牙袋深度减少的平均值分别为1.9mm、0.8mm和2.7mm

1. The purpose of this study is to investigate the histological responses of periodontal tissue to hydroxyapatite ceramic (Periograf^< <ﾟ!> >) implanted into vertical bone defects in rats.ResultsAt 10 days, bone matrix formation had begun on the surface of the apatite. At 40 days, newly formed bone tissue around the apatite demonstrated differentiation of osteoblasts followed by the formation of collagen fibers and osteoids with many small, round deposits of bone crystals.2. Seventy-five patients who participated in a clinical study comparing the response of periodontal osseous defects to either grafting with Periograf^< <ﾟ!> > ceramic or debridement only were followed under an active maintenance program for six-months.The results are as follows.(1.) In the experimental groups, the mean values for gingival recession, gain of attachment level, decrease of pocket depth and roentgenographic bone fill were respectively 1.8mm, 2.0mm, 3.7mm and 62.2% at six months postoperativery.(2) In control groups, the mean values for gingival recession, gain of attachment level and decrease of pocket depth were respetivery 1.9mm, 0.8mm and 2.7mm