Design and Development of HIV-1 Integrase Inhibitors Based on a Natural Product Lead

艾滋病毒/艾滋病是一个严重的健康问题，全世界有4000多万艾滋病毒感染者。对当前药物的抗药性正在迅速上升，迫切需要新的治疗方法。该项目将汇集当地在有机合成和病毒学方面的专门知识，以便开发新的更好的艾滋病毒/艾滋病治疗方法。最终，澳大利亚艾滋病毒携带者可能直接受益于生产的抗艾滋病毒化合物，也可能受益于我们对该项目产生的这种难以捉摸的病毒的了解取得的进展。

HIV/AIDS is a significant health problem with over 40 million people infected with HIV worldwide. Resistance to current drugs is rising rapidly and new therapeutics are urgently needed. This project will bring together local expertise in organic synthesis and virology in order to develop new and better treatments for HIV/AIDS. Ultimately, Australians with HIV may benefit directly from anti-HIV compounds produced and may also benefit from advances in our understanding of this elusive virus resulting from the project.