Femtosecond lasers for plasma-assisted micro material processing and bioprocess technology.

飞秒激光器是现代光子学和非线性光学的基本元件。应用包括工业计量、表面处理、光谱学、显微镜和医学。如果由于成本和空间的原因，具有窄参数范围的紧凑系统在工业应用中是优选的，则通常需要具有大参数空间的系统用于研究。申请的飞秒激光将用于研究，该研究在自然科学与技术学院的应用科学与艺术大学希尔德斯海姆，霍尔茨明登，哥廷根的研究重点“激光和等离子体技术”中进行。大部分的研究是在：o表面改性（例如功能化、微结构化）（例如金属、聚合物、玻璃、生物材料）; o飞秒激光技术在生物过程工程和医学中的应用。HAWK被放置在这个大型设备的位置上，研究o在热敏衬底上进行高效率和形状保真度的微材料加工;o飞秒激光辐射与大气压等离子体相结合用于微材料加工的相互作用机制; o基于飞秒激光的眼科诊断和治疗方法;o基于飞秒激光的基因组学/结构生物学方法。这些项目所需的210-1030 nm的大波长范围与50 nJ以上的高脉冲能量相结合，可以通过光纤激光泵浦的光参量放大器实现，随后产生二次和三次谐波。申请的大型装置的详细规格来自“德国研究基金会”和“联邦教育和研究部”资助项目的结果。该系统非常适合当前和计划中的研究项目。模块化设计通过集成额外的模块，确保在其他应用领域（例如3光子成像、使用“泵浦和探测”方法确定寿命）的可持续使用和应用。

Femtosecond lasers are fundamental elements in modern photonics and nonlinear optics. Applications include industrial metrology, surface treatment, spectroscopy, microscopy and medicine. If compact systems with a narrow parameter regime are preferred in industrial applications for reasons of cost and space, systems with a large parameter space are often required for research. The femtosecond laser applied for will be used in research, which is carried out in the research focus "Laser and Plasma Technology" of the University of Applied Science and Arts Hildesheim, Holzminden, Goettingen at the Faculty of Natural Science and Technology. The majority of the research is carried out on: o surface modification (e.g. functionalization, micro structuring) of solids (e.g. metals, polymers, glasses, biological materials) by combined plasma action; o application of femtosecond laser technology in bioprocess engineering and medicine.The HAWK is put in a position with this large device, to investigateo micro material processing with high efficiency and shape fidelity also on thermally sensitive substrates;o the interaction mechanisms of femtosecond laser radiation in combination with atmospheric pressure plasma for micro material processing;o femtosecond laser-based diagnostic and therapeutic methods for ophthalmology;o femtosecond laser-based methods for genomics/structural biology.The large wavelength range of 210-1030 nm required for the projects in combination with high pulse energies above 50 nJ can be realized by a fiber laser pumped Optical Parametric Amplifier with a subsequent second and third harmonic generation. A detailed specification for the large device applied for was derived from the results of “German Research Foundation” and “Federal Ministry of Education and Research”-funded projects. The system fits perfectly into current and planned research projects. A modular design ensures sustainable use and application in other application fields (e.g. 3-photon imaging, lifetime determination using "pump & probe" methods) by integrating additional modules.