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Multi Photon Microscope without laser

Multi Photon Microscope without laser
无激光多光子显微镜
批准号:
446639256
负责人:
金额:
$0.0万
依托单位:
依托单位国家:
德国
项目类别:
Major Research Instrumentation
财政年份:
2020
资助国家:
德国
项目状态:
未结题
起止时间:
2019-12-31 至 --

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中文摘要
翻译
作为普通动物学和神经生物学系,我们申请多光子显微镜,以建立与细胞和功能神经生物学相关的新科学项目。活组织和行为动物中分子过程的可视化是了解活脑的最有前途的方法之一。目前和未来的项目是研究神经网络调制与癫痫、共济失调和焦虑等疾病的重要性。我们将应用光遗传学工具和遗传编码传感器,这已经在我们的部门开发,在体外和体内可视化和控制G蛋白受体信号。多光子显微镜将是一个多用户设施,可供教师和大学内的其他用户使用。
英文摘要
We, as the Department of General Zoology and Neurobiology, apply for a multi-photon microscope to establish new scientific projects related to cellular and functional neurobiology. The visualization of molecular processes in living tissue and behaving animals is one of the most promising methods to understand the living brain. Current and future projects are the investigation of the importance of neuronal network modulation in relation to diseases such as epilepsy, ataxia and anxiety. We will apply optogenetic tools and genetically encoded sensors, which have been developed in our Department, to visualize and control the G protein receptor signals in vitro and in vivo. The multi photon microscope will be a multi user facility, which will be available for the other users within the faculty and university.
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