The comprehensive study of indoor environment and residents' health, considering chemical sensitivity

为了研究室内环境和污染物水平的变化，我们在北海道组成了两个队列进行跟踪。甲醛有夏季升高、冬季降低的趋势。我们认为新建房屋中的甲醛水平最高，但结果并不支持这一点。调查化学敏感型(CS)患者个人暴露量的纵向变化，观察其个人暴露量的季节/月趋势。虽然根据主动和被动采样的结果，CS相关症状的康复与醛和挥发性有机化合物(VOCs)的浓度之间没有关系，但一些化学物质可能是导致这些症状的原因。2001年在旭川建造了一座CS治疗室。每个房间的甲醛浓度在施工后不久和此后都低于20 ppb。挥发性有机碳水平也很低。在化学污染方面，房子的室内环境对CS来说是好的。在CS之家开始治疗的患者对住在CS之家和室内环境都比较满意。我们在Izu.我们也进行了类似的研究。我们试图根据扩散采样器的几何形状(扩散面积和扩散长度)和基于Fick扩散定律的VOCs的物理性质来推导扩散采样器的采样率(SR)。同时采用有源(泵浦)和扩散采样的方法测定了受激拉曼散射。对于大多数采样器和大多数VOCs，理论确定的SRS与实验确定的SRS几乎相同。根据扩散理论精确计算VOCs的受激拉曼散射似乎是可能的，而不需要进行实验测量。

In order to study the indoor environment and the change in pollutant levels, we formed two cohorts to follow in Hokkaido. Formaldehyde has a tendency to become higher in the summer and lower in the winter. We supposed that formaldehyde levels in newly built houses are the highest, but results don't support it. The furniture which residents brought into the house might contribute to formaldehyde concentration.We investigated the longitudinal change of personal exposure levels for chemical sensitivity (CS) patients, and observed the seasonal/monthly trends in their personal exposure levels. No relationship between the recuperation of CS-related symptoms and the concentrations of aldehyde and volatile organic compounds (VOCs) was recognized ; although, based on the results from active and passive sampling, some of the chemicals may be responsible for the symptoms.A CS treatment house was built at Asahikawa in 2001. The formaldehyde concentration in each room was less than 20 ppb just after the construction and since then. VOC levels were also low. The indoor environment of the house is good for CS with regard to chemical contamination. Patients who started their treatment stay at the CS house were fairly satisfied with staying at the house and with indoor environment. We also conducted the similar study at Izu.We tried to derive the sampling rate (SR) for diffusion samplers from the geometry (diffusion area and diffusion length) of the samplers and the physical properties of VOCs based on Fick's law of diffusion. SRs were also determined experimentally using simultaneous active (pump) and diffusion sampling. For most samplers and most VOCs, the theoretically determined SRs were nearly the same as the experimentally established SRs. Accurate calculation of SRs for VOCs based on the diffusion theory seems possible without the need to perform experimental measurements.