Development of the fibrointegrated implant
Development of the fibrointegrated implant
批准号:
10557160
负责人:
INOUE Takashi
金额:
$7.87万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B).
财政年份:
1998
资助国家:
日本
项目状态:
已结题
起止时间:
1998 至 2000
中文摘要
种植体的成败取决于对骨集成公司的收购。尽管种植体周围骨结合牢固,但种植体周围软组织的防御机制并不比天然牙更远,这就是种植体周围炎容易诱发且始终存在坠落危险的原因。从这个角度来看,本项目提出的纤维结合种植体牢固地附着在上皮下的结缔组织似乎对防止骨吸收具有重要意义。为了人工制造尖锐的纤维,在给予种植体颈部的表面进行了修复。种植体表面粗糙度约为3μm,得到孔洞大于50μm的种植体为锋利纤维的组织是有效的信息,并对影响纤维附着的表面质量进行了研究。对考虑表面电荷的表面设计进行了尝试。对镜面的纯钛板进行离子注入处理(Ca+、N+、F+)、阳极化处理、二氧化钛低温热喷涂处理、离子镀处理(TiN、Al_2O_3)、离子束混合处理耐磨表面处理(银、锡、锌、铂),获得了基础数据。指出了研制停止应用含漱口药物、诱导抗体阻止细菌黏附或细菌黏附的人工唾液的必要性,包括临床应用。
英文摘要
The success or failure of the dental implant depends on the acquisition of the firm osseointegration. Eventhough, firm osseointegration was achieved, the defense mechanism of soft tissue around the implant does not exist further than the natural tooth and this is the reason why peri-implantitis is easy to be induced and always has the danger of the falling. From this point of view, the firm attachment of the connective tissue under the epithelium by fibrointegrated implant raised by this project seems to be important in order to prevent the bone resorption. The retrieval was advanced on the surface given to the implant cervix in order to artificially make the sharpy fiber. It had the ruggedness of about 3 μm as a surface shape on the implant surface, and information of being effective in order to form the organization that the implant as an aperture with the hole over 50 μm is sharpy fibers was obtained.On the surface quality with the effect in the fibrous attachment, the modification was studied. Surface design considering the surface charge was tried. It was possible that it conducted ion implantation processing (Ca+, N+, F+), anodization, titania low temperature thermal spraying processing, ion plating processing (TiN, Alumina), abrasion resistant surface treatment of ion beam mixing processing (Ag, Sn, Zn, Pt) to the pure titanium plate of the specularity and obtains basic data.The necessity of the development of the artificial saliva which will stop application of gargling and mouth rinsing medicine, induction of the antibody which stops the bacteria adhesion or bacteria adhesion including clinical application in future is indicated.
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Yoshinari, M., Oda, Y., Ueki, H., Yokose, S: "Immobilization of bisphosphonates on surface modified titanium"Biomaterilas. 22. 709-715 (2001)
Yoshinari, M.、Oda, Y.、Ueki, H.、Yokose, S:“双膦酸盐在表面改性钛上的固定化”生物材料。
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通讯作者:
宮山直也: "ドライプロセスによるインプラント用チタン表面改質"歯科材料・器械. 18. 109-121 (1999)
Naoya Miyayama:“通过干法工艺对种植体进行钛表面改性”《牙科材料和仪器》18. 109-121 (1999)。
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通讯作者:
Ayukawa,Y.et al.: "An Immunocutochemical study for lysosomal cathepsins Band D related to the intracellular degradation of titanium at the bone-titanium interface" J. Periodontol. 69. 62-68 (1998)
Ayukawa,Y.等人:“溶酶体组织蛋白酶带 D 与骨-钛界面处钛的细胞内降解相关的免疫皮肤化学研究”J. periodontol。
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通讯作者:
Inoue,T.: "Implant bone tissue interface"Bull Kanagawa Dent.. 27. 132-141 (1999)
Inoue,T.:“植入骨组织界面”Bull Kanakawa Dent.. 27. 132-141 (1999)
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通讯作者:
Yoshinari, M., Inoue, T.: "Surface Modification of dental implant"Surface Science. 20. 613-620 (1999)
Yoshinari, M., Inoue, T.:“牙种植体的表面改性”表面科学。
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