Inductively Coupled Plasma Triple-Quad Mass Spectrometer and Chromatography (LC-ICP-QQQ)

萨尔兰大学元素分析的一个重点是通过电感耦合等离子体质谱法（ICP-MS）进行痕量分析，以及通过ICP-MS耦合进行元素形态分析，特别是与毛细管电泳（CE）和液相色谱法（LC）耦合。电感耦合三重四极杆质谱仪（LC-ICP-QQQ）用于水溶液中元素和元素形态的高灵敏痕量分析，这对分析提出了很大的挑战，特别是在复杂的环境样品中。该应用程序可替代现场过时的ICP MS。该仪器将成为处置库研究领域各种研究项目的主要分析工具（痕量分析，调查与储存有关的元素的流动性及其与天然有机物的形态形成），水监测（小型水道中污染物的数量、形态和来源）、医学（痕量分析，以检测纳米颗粒在各种组织中的分布和积累），功能材料（金属包覆抗菌剂的多元筛选和浸出行为）和材料科学（确定和验证内部开发的纳米级材料的化学成分、功能化程度和分解行为）。所提出的LC-ICP-QQQ可以使用，由于其高性能（特别是元素痕量分析和元素形态通过LC耦合）和扩展的测量范围（在NanoBioMed领域的应用）的各种当前和新的研究项目在萨尔兰大学。

One focus of elemental analysis at Saarland University is trace analysis by means of mass spectrometry with inductively coupled plasma (ICP-MS) and elemental speciation by coupling of ICP-MS, in particular with capillary electrophoresis (CE) and liquid chromatography (LC). The requested inductive coupled triple-quadrupole mass spectrometer with coupled liquid chromatography system (LC-ICP-QQQ) is used for the highly sensitive trace analysis of elements and element species in aqueous solutions, which pose a great challenge for analysis, especially in complex environmental samples. The application is a replacement for the outdated ICP MS at the site. The instrument will be a major analytical tool in various research projects in the fields of repository research (trace analysis to investigate the mobility of repository-relevant elements and their speciation with naturally occurring organic matter), water monitoring (quantification, speciation and origin of pollutants in small watercourses), medicine (trace analysis to detect the distribution and accumulation of nanoparticles in various tissues), functional materials (multi-element screening and leaching behaviour of metal-coated antibacterial) and materials science (determination and verification of the chemical composition, degree of functionalisation and decomposition behaviour of nanoscale materials developed in-house). The proposed LC-ICP-QQQ can be used due to its high performance (especially for element trace analysis and element speciation through LC-coupling) and extended measurement range (applications in the field of NanoBioMed) for various current and new research projects at Saarland University.