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High-speed Ultracentrifuge Facility with Sensitive Scanning Optics for the Analysis of Interacting Biomolecules

High-speed Ultracentrifuge Facility with Sensitive Scanning Optics for the Analysis of Interacting Biomolecules
具有灵敏扫描光学器件的高速超速离心机,用于分析相互作用的生物分子
批准号:
LE0560722
负责人:
A/Prof Geoffrey Howlett
金额:
$34.19万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Linkage Infrastructure, Equipment and Facilities
财政年份:
2005
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2005-01-01 至 2006-12-31

项目摘要

项目成果

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中文摘要
翻译
这个要求是一个高速分析超离心机配备敏感的吸光度,荧光和干涉扫描光学。该设备是澳大利亚首个此类设备,将建立一个世界级的设备,用于分析大分子复合物的大小、形状和稳定性及其在溶液中的相互作用。这个新设备将能够高通量筛选有潜力成为新药的小分子。这一核心平台技术将涵盖从基础研究到发现商业化的一系列需求。这些设备将支持现有的高质量生物技术研究项目,并为研究生培训和国际合作提供新的机会。
英文摘要
This request is for a high-speed analytical ultracentrifuge equipped with sensitive absorbance, fluorescence, and interference scanning optics. The equipment, the first of its kind in Australia, would establish a world-class facility for analysing the size, shape, and stability of macromolecular complexes and their interactions in solution. This new facility will enable high through-put screening of small molecules with potential as new drugs. This core platform technology will cover the range of needs from basic research through to commercialization of discovery. The equipment will support existing high quality research projects in biotechnology and provide new opportunities for post-graduate training and international collaboration.
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Biophysical identification of natural human antibody targets
  • 批准号:
    LP100100392
  • 项目类别:
    Linkage Projects
  • 资助金额:
    $20.9万
  • 财政年份:
    2010
  • 负责人:
    A/Prof Geoffrey Howlett
  • 依托单位:
Macromolecular Self-Assembly of Amyloid Fibrils
  • 批准号:
    DP0877800
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $29.7万
  • 财政年份:
    2008
  • 负责人:
    A/Prof Geoffrey Howlett
  • 依托单位:
Protein-protein interactions in amyloid deposits
  • 批准号:
    DP0449510
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $25.07万
  • 财政年份:
    2003
  • 负责人:
    A/Prof Geoffrey Howlett
  • 依托单位:
海外基金