Large-scale knowledge information processing in genome analysis

优先领域“基因组信息学”科学研究项目旨在为人类和其他生物体的基因组研究开发新的计算技术。特别是，该项目侧重于(i)如何组织和整合基因组分析产生的不同类型数据的数据库问题和（ii）如何破译编码在序列数据中的生物学意义的计算问题，这些序列数据是通过实验得到的最终产品。在这五年中，我们发表了100多篇原创论文，以及三卷本的基因组信息学系列论文集。我们还出版了一些日文的原创和评论论文、文件、小册子和书籍。该项目有助于建立GenomeNet计算机网络，作为日本生物医学研究的信息学基础设施，并通过定期组织讲习班和教程培养生物信息学研究界。基础研究成果，特别是数据库问题的基础研究成果，已作为实用数据库和软件产品实施，作为GenomeNet数据库服务的一部分在国际上提供。

The Scientific Research Project on the Priority Area "Genome Informatics" aimed at developing new computational technologies for genome research on human and other organisms. Especially, the project focused on (i) the database problem of how to organize and integrate different types of data being produced by genome analyzes and (ii) the computational problem of how to decipher biological meaning encoded in the sequence data which is the final product by experiments. During the five year period, we published more than 100 original papers in addition to the three volumes of the Genome Informatics Series Proceedings. We also published a number of original and review papers, ducuments, pamphlets, and books in Japanese. The project has been instrumental in establishing the GenomeNet computer network as the informatics infrastructure for biomedical research in Japan and in nurturing the bioinformatics research community by regularly organizing workshops and tutorials. The basic research results, especially for the database problem, have been implemented as practical databases and software products that are internationally made available as a part of the GenomeNet database service.