Synthesis of conjugated polyynes by alkyne metathesis

共轭多炔的合成是当今一个真正的科学挑战。尽管在过去的几十年里已经报道了几种方法，但用于合成具有两个以上共轭CC三键的化合物的多样化和高效的方法仍然不够。在这个项目中，我们建议使用炔烃复分解作为一种新的“软”和方便的方法来合成三炔、四炔、戊炔和其他化合物。在对三炔类化合物取得初步研究成果的基础上，我们提出了新的催化剂，旨在控制目标多炔类化合物的选择性。在评估了我们的方法的范围和局限性之后，它将被应用于目前物理有机化学领域的已知方法无法获得的聚炔的合成。该项目的最终目标是合成C24，这是一种碳的循环同素异形体。

The synthesis of conjugated polyynes is a genuine scientific challenge nowadays. Although several methods have been reported over the last decades, diverse and efficient methods for the synthesis of compounds bearing more than two conjugated CC triple bonds remain inadequate. In this project, we propose to use alkyne metathesis as a new "soft" and expedient method for the synthesis of triynes, tetraynes, pentaynes and beyond. On the basis of promising preliminary results obtained with triynes, we proposed new catalysts that are designed to control the selectivity towards the targeted polyynes. After evaluating the scope and limitations of our methodology, it will be applied to the synthesis of polyynes that are currently inaccessible with known methods in the field of physical organic chemistry. An ultimate goal of the project is the synthesis of C24, a cyclic allotrope of carbon.