An experimental investigation and Dynamic model of learning & memory

通过理论和实验证据，参与记忆编码和处理的信息(编码)在海马皮层系统中的表达已经变得明显。具体地说，Tsukada等人。已经证明时空学习规则在暂时存储海马神经网络中CAL回路的突触权重空间中的时空模式方面是有效的(Tsukada等人，1996,1998；Tsukada，2004；Tsukada等人，2005；Aihara等人，2005；Tsukada和潘，2005)。在听觉皮质中，已经发现在感觉信息和海马信息之间存在时间依赖的门控(时间窗)(Yamamoto等人，1999，Miyazaki等人，2005)。抑制性和兴奋性修饰是由于听觉区域的活动而产生的，而听觉区域的活动受海马CA1区活动结构的调节，这一事实表明，关于…信息的复杂信息处理是可能的更多的来自海马体，它编码在大脑皮层听觉区域。此外，我们还使用电压敏感光学记录方法，成功地测量了声音和电击恐惧条件反射学习前后听觉皮质的可塑性反应，随着条件频率的增加，响应场增大，而在非条件频率下，响应场没有显著变化(Miyazaki等，2005)。在实验结果的基础上，建立了模型，得到了以下结论。当背景信息从海马体输入时，随着感受野的扩大，编码和加工时间显著改善，记忆模式的正确率也增加(Tsukada和潘，2005)。感受野的扩大解释了为什么当呈现CS音调时，在实验中，听觉皮质的反应面积显着增加。较少

Through theory and experimental evidence, the expression of information (coding) involved in the encoding and processing of memory in the hippocampal cortical system has become evident. Specifically, Tsukada et al. have shown that the spatiotemporal learning rule is effective in temporarily storing a spatiotemporal pattern in the synaptic weight space of the CAl circuit in the hippocampal neural network (Tsukada et al.,1996, 1998; Tsukada,2004; Tsukada et al., 2005; Aihara et al.2005; Tsukada and Pan,2005).In the auditory cortex, it has been revealed that a timing dependent gating (timing window) exists between sensory information and hippocampal information (Yamamoto et al., 1999, Miyazaki et al., 2005). The fact that inhibitory and excitatory modifications are generated in response to the activity of the auditory area which is regulated by the structure of activity in the hippocampal CAlarea, signifies that the processing of complex information is possible in regards to information f … More rom the hippocampus which is encoded in the cerebral cortex auditory area. In addition, we were successful in measuring the plastic responses of the auditory cortex before and after the learning of fear conditioning with sound and electric shock by using the voltage sensitive optical recording method.With a conditioned frequency, the responsive field enlarged, while with unconditioned frequencies, there was no significant change in the responsive field (Miyazaki et al., 2005). Based upon experimental results, the model was constructed which resulted in the following. When context information was inputted from the hippocampus, along with an enlargement of the receptive field the encoding and processing time improved considerably, and the correct rate of the memory pattern also increased (Tsukada and Pan, 2005). The enlargement of the receptive field explains why the significant increase in the response area in the auditory cortex was seen in experimentation when the CS tone was presented. Less