Downsizing studies on chemical experiments for minimization of environmental loads

结合我国环境、健康、安全废物管理的现状，将高校实验室化学实验废物减量化学术教育活动作为本项目或重点领域科研项目的名称是恰当的。结论是，研究活动将对该项目的新术语提出建议，并将“缩小化学实验规模”作为这一重大学术研究项目的研究活动的关键词。将微柱集成到微型高效液相色谱系统中，以减少有害有机溶剂。研制了一种用于空气中痕量气体监测的微型芯片装置。为实现对大气中二氧化氮(NO2)的高灵敏度测量，研制并优化了微型测量装置。在风洞中，检测下限约为1 ppb。该微量气体测量芯片由两个聚甲基丙烯酸甲酯…组成更多的e板和聚四氟乙烯过滤器作为吸收区域。采用注塑成型的方法制作微通道。在优化的条件下，对微芯片装置进行了NO2的测试，并与常规仪器测量的数据进行了比较。本项目还进行了用于有机合成的微型反应器的开发。研制了一种同时测定柴油机尾气颗粒物中苯并[a]芘(BaP)和苯并[k]荧菲(BKF)的装置和净化芯片。净化芯片可使柴油机排气颗粒物溶液中BaP和BKF的回收率达到90%以上。将净化芯片与检测装置相结合，可使检测时间比常规方法缩短不到十分之一。将柴油机尾气颗粒物(DEP)中的多环芳烃(PAHs)捕获到硅胶微珠中，然后将硅胶微珠装入芯片中，然后提取到氯仿中。开发了一种微芯片反应器前处理系统，用于DEP中多环芳烃的洗脱。这些用微型仪器进行的化学实验结果与普通的大块实验方法是一致的。较少

Academic educational activities for decresing experimental wastes on chemical experiments in university laboratories were proper as the title of this program or the scientific research of priority area project, considering the present situations of the environmental, health and safety waste management issues. It was concluded that the research activities would give their suggestion about the new term to the project, considering "downsizing on chemical experiments" to be the key word of the research activities of the important academic research program.Microcolumns were integrated into the micro HPLC systems to reduce hazardous organic solvents. A microchip device for monitoring of the trace gas in the air was developed. The micro device has been developed and optimized in order to measure for atmospheric nitrogen dioxide (NO_2) with high sensitivity. The detection limit was approximately 1 ppb in wind tunnel. The trace gas measurement microchip was composed of two polymethylmethacrylat … More e plates and polytetrafluoroethylene filter as absorbing area. Microchannel was fabricated by injection molding. Under optimized conditions, the microchip-device was tested measurement of NO_2. Comparison with the date generated by the conventional instrument indicated with agreements. Development of a micro reactor for organic synthesis was also carried out in this program. We developed a device for simultaneous determination of benz[a]pyrene (BaP) and benzo[k]fluoranthene (BkF) in diesel exhaust particles and clean-up microchip for pretreatment. About more than 90% of recovery of BaP and BkF in diesel exhaust particle solutions was attained by the clean-up microchip. Combining the clean-up microchip and detection device, detection time could be shortened less than one tenth compared with the conventional method. PAHs in diesel exhaust particle (DEP) were trapped into silica gel beads, which were packed into the microchip, and extracted into chloroform. Pre-treatment system with a microchip reactor was developed for eluting PAHs from DEP. These chemical experimental results with micro scale tools obtained were the same as ordinary bulk scale methods. Less