Design and Development of Multimetallic Reagents and Their Application in Synthetic Reactions

这项研究计划讨论了过渡金属和主族金属的各种组合对合成有机转化催化剂的协同效应。重点介绍了过渡金属/主族金属或过渡金属/过渡金属协同催化剂在碳-碳键形成反应中的应用。这里描述了该研究计划的代表性结果：铁催化的选择性联芳基交叉偶联反应和铁催化的卤代烷与各种有机金属试剂的交叉偶联反应，包括有机镁、锌、硼和铝化合物。

This research program dealt with synergistic effects of various combinations of transition and main group metals on the catalyses for synthetic organic transformations. We focused, in particular, on transition metal/main group metal, or transition metal/transition metal cooperative catalysts upon carbon-carbon bond formation reactions. Herein are described representative results of the research program: iron-catalyzed selective biaryl cross-coupling and iron-catalyzed cross-coupling reaction of haloalkanes with various organometallic reagensts, including organomagnesium, zinc, boron, and aluminum compounds.