Contact X-ray Cabinet

接触式x光机是骨科研究中许多常规方法所需要的，是我们研究所必不可少的基础设备。申请的设备是为了替换现有的x光柜，该x光柜已达到使用寿命，因此无法进行维护和维修。备件也不再可用，目前使用的x射线管只有非常有限的剩余寿命，这就是为什么迫切需要及时更换。该研究所目前几乎所有的研究项目都需要一个功能正常的x射线箱。应用范围非常广泛，从样品切割的定向辅助，某些样品制备过程的控制，如脱钙，识别大型和小型动物模型的表型，到可直接用于出版物的图像和数据的生成，如骨密度和骨骼形态的量化。此外，还有与其他各种研究所和设施的合作项目，所有这些项目都依赖于一个功能良好的x光箱，以便研究肌肉骨骼问题或用该设备检查根本不同的方面。这些包括，例如，神经组织中的异位矿化或检查软组织的对比。这里应用的接触式x射线柜与之前可用的设备相比有一些决定性的改进：x射线管的最大电压可以达到100千伏，这大大改善了极其紧凑样品的显示，特别是金属植入物的显示。此外，极大地扩大了43 x 43厘米的传感器面积，比只有12 x 12厘米的旧传感器具有相当大的优势。更大的人类样本（如法医骨学、膝关节或髋关节植入物）或大型动物模型样本可以一体展示，从而实现更有效和有意义的检查。但即使是较小的样本，这种传感器尺寸也提供了决定性的优势，因为可以同时显示多个样本进行直接比较。所要求设备的扩展功能还可以开发和建立新的创新分析方法，例如在小动物模型中集成，自动化骨密度测量和身体成分测定。因此，迫切需要所需的接触式x射线柜，以确保在基础、转化和临床研究以及法医领域的众多项目的成功处理，并确保我们研究所未来的高科研绩效。

The contact x-ray cabinet is required for numerous routinely used methods in osteological research and is an essential basic equipment for our institute. The device applied for is intended to replace an existing X-ray cabinet that has reached the end of its service life and can therefore neither be serviced nor repaired. Spare parts are also no longer available and the X-ray tube currently in use only has a very limited remaining lifespan, which is why timely replacement is urgently required. A functioning X-ray cabinet is required for almost all current research projects at the institute. The applications are very well established and range from orientation aid for sample cutting, control of certain sample preparation processes such as decalcification, identification of phenotypes in large and small animal models, to the generation of images and data that can be used directly for publications, such as bone density and quantification of the skeletal morphology. Furthermore, there are also cooperation projects with various other institutes and facilities, all of which are dependent on a functioning X-ray cabinet in order to work on musculoskeletal questions or to examine fundamentally different aspects with the device. These involve, for example, ectopic mineralization in neuronal tissue or checking the contrasting of soft tissue. The contact X-ray cabinet applied for here has some decisive improvements over the previously available device: The maximum X-ray tube voltage can reach up to 100 kV, which significantly improves the display of extremely compact samples and, in particular, of metallic implants. Furthermore, the enormously enlarged sensor area of 43 x 43 cm has considerable advantages over the old one with only 12 x 12 cm. Larger samples of human origin (e.g. forensic osteology, knee or hip implants) or from large animal models can be displayed in one piece, which enables more efficient and meaningful examinations. But even with smaller samples, this sensor size provides a decisive advantage, as several samples can be displayed in direct comparison at the same time. The extended capabilities of the requested device also enable the development and establishment of new and innovative analysis methods, such as integrated, automated bone density measurement and body composition determination in small animal models. Thus, the requested contact x-ray cabinet is urgently needed to ensure the successful processing of numerous projects in the areas of basic, translational and clinical research as well as in forensics and to ensure the high scientific research performance of our institute in the future.