Calcium signalling in neurons of the central nervous system

理解构成大脑和中枢神经系统的神经元之间的细胞间通讯过程对于我们理解诸如自主和反射运动、感觉反应以及学习和记忆等基本现象至关重要。我们希望更好地了解钙如何控制神经元和突触功能。 这些研究将联合收割机结合高速荧光成像、电生理记录、使用腺病毒和辛德比斯病毒的基因转移以及基因设计和靶向生物传感器来描述中枢神经系统神经元产生的钙信号的关键“描述符”？谈话？彼此之间

Understanding of the processes of cell-to-cell communication between neurons that comprise the brain and central nervous system is of primary importance to our understanding of fundamental phenomena such as voluntary and reflex movement, sensory responses and learning and memory. We would like to obtain a better understanding of how calcium controls neuronal and synaptic function. These studies will combine high-speed fluorescence imaging, electrophysiological recording, gene transfer using Adeno- and Sindbis viruses, and genetically designed and targeted biosensors to describe key "descriptors" of the calcium signals generated as neurons of the central nervous system ?talk? to each other.