Molecular Cell Biology and Comparative Genomics Of Planctomycetes and Verrucomicrobia In Relation To Evolution Of Cytoskeletal Proteins and Membrane-bounded Compartments

plantomytes和verrucomicrobia是进化上不同的细菌群，它们具有不同的细胞结构，并与真核生物共享一些重要的细胞生物学基因，例如verrucomicrobia的细胞骨架蛋白微管蛋白。这些细菌对于理解通过细胞骨架蛋白运动从简单细胞分裂的无核细胞到染色体分离的有核细胞的转变很重要。本项目将比较plantomycetes和verrucomicrobia的基因组，确定它们之间的关系，确定verrucomicrobia的微管蛋白同源物是否可以形成细胞骨架结构，表征氨氧化plantomyetes用于废水处理的细胞骨架。

Planctomycetes and verrucomicrobia are evolutionarily distinct groups of bacteria which possess unusual cell structure and which share some significant genes important in cell biology with eukaryotes e.g. in verrucomicrobia the cytoskeleton protein tubulin. These bacteria are important for understanding the transition from non-nucleated cells with simple cell division to nucleated cells with chromosome separation via cytoskeletal protein movement.The project will compare genomes of of planctomycetes and verrucomicrobia to determine their relationship, determine whether the tubulin homolog of verrucomicrobia can form cytoskeleton structures, and characterize the cytoskeleton of ammonium-oxidizing planctomycetes used in wastewater treatment.