A study on a method for ddiagnosing arteriosclerosis by means of pulse wave velocity

检测了可能降低动脉顺应性的疾病患者（患者）与正常人（正常人）之间动脉脉搏波速度（PWV）的差异。首先，检查可能影响PWV的生理因素。有统计学意义的因素是年龄、收缩压和舒张压。其次，通过多元回归分析，得到了一个线性预测函数，可以预测PWV通过上述因素，并通过该函数计算值减去测量PWV。最后，将正常人的这些残差与每种疾病类别中的患者的残差进行比较，并计算残差与每种血清脂质测量值之间的相关系数，即，检查所有受试者的总胆固醇、磷脂、甘油三酯和β-脂蛋白。因此，在正常人和患者的PWV之间没有发现显著差异，并且在PWV和每种血清脂质水平之间没有获得显著相关性。

Difference of arterial pulse wave velocity (PWV) between patients with diseases that might decrease the arterial compliance (patient) and subjects without those diseases (normals) was examined. First, physiological factors that might influence PWV were examined. The statistically significant factors were age, systolic blood pressure, and diastolic blood pressure. Second, a linear predicting function that could predict PWV by means of the above mentioned factors was obtained by multiple regression analysis, and the values computed by this function were subtracted from the measured PWVs. Finally, these residuals of the normals were compared with those of the patients in each disease category, and a correlation coefficient between the residuals and the measurements of each serum lipids, i.e., total cholesterol, phospholipid, triglyceride, and beta-lipoprotein was examined for all the subjects. Consequently, no significant difference was found between PWVs of the normals and those of the patients, and no significant correlation was obtained between PWV and each of serum lipid levels.