Experimental and Clinical Study of Auditory Evoked Potentials

1.内侧膝状体记录的近场电位表现为大的负波(N6)，潜伏期与P6相容(8.57；正负0.88毫秒)。损毁内侧膝状体后，P6和N6波幅分别降至65%和90%。这一结果表明，内侧膝状体主要与远场电位的P6波有关。在初级听皮层AI和AII，记录到大的负波(N7)，潜伏期与P7相容(11.08；正负1.08毫秒)。去单侧听皮质AI和AII后波幅分别降至51.7%(P7)和39.1%(N7)，切除双侧听皮质后波幅分别降至81.7%(P7)和77.6%(N7)。这些数据表明，初级听皮层AI和AII主要与远场电位的P7波有关。在内侧膝状体记录到17个对短声刺激呈现时间锁定反应的单位反应。这些单位反应由正、负波组成，正、负波的峰潜伏期分别对应于N7(0.221毫秒)和P7(10.7；正负0.1ms)。与损伤研究相反，单位反应显示内侧膝状体的活动主要与P7w4有关。从初级听觉皮层AI获得了14个对短声具有时间锁定反应的单位反应。单位反应的正负波峰潜伏期分别为8.05正负0.05毫秒和10.90正负0.93毫秒。正波和负波的潜伏期分别为N7(8.7±0.1ms)和P7(10.71+-0.66msec)。这表明初级听觉皮质AI的活动也与P7有关

1. Near field potentials which were recorded from the medial geniculate body showed large negative wave (N6) with latency, compatible with P6 (8.57 <plus-minus>0.88 msec). After making lesion in the medial geniculate body, amplitudes of P6 and N6 decreased to 65 % and 90 %, respectively. This result indicate that the medial geniculate body is mostly related to P6 wave of the far field potential2. In the primary auditory cortex AI and AII, large negative wave (N7) was recorded with latency, compatible with P7 (11.08 <plus-minus>1.08 msec). These waves decreased to their amplitudes to 51.7 % (P7) and 39.1 % (N7) after the removal of the unilateral auditory cortex AI and AII, and to 81.7 % (P7) and 77.6 % (N7) after the bilateral removal. These date shows that the primary auditory cortex AI and AII are mostly related to P7 wave of the far field potential3. Seventeen unit responses which showed time locked response to click stimuli were recorded from the medial geniculate body. These unit response consisted of the positive and negative waves and peak latencies of the positive and negative waves were corresponding to N7 (8.7 <plus-minus> 0.221 msec) and P7 (10.7 <plus-minus>0.1 msec), respectively. Contrary to the lesion study, unit responses showed that activities of the medial geniculate body were mostly related to P7 w4. Fourteen unit responses which showed time locked response to click were obtained from the Primary auditory cortex AI. The respective peak latencies of positive and negative waves of unit response were 8.05 <plus-minus>0.05 msec and 10.90 <plus-minus>0.93 msec. The positive and negative waves were mostly related in latencies to N7 (8.7 ([SY.+-.[)0.1 msec) and P7 (10.71 <plus-minus> 0.66 msec), respectively. This indicate that activities of the primary auditory cortex AI are also related to P7