Physiological Function of Polyamines Which are Covalently Linked to Peptidoglycan in Bacteria

摘要在严格厌氧的乳酸发酵菌中，发现了与细胞壁肽聚糖共价连接的多胺。分离到的菌株包括反刍月形单胞菌（Selenomonasruminantiom）、反刍月形单胞菌（S. sputigena、Veillonellaalcalescens、V parvula、Anaerovibrio lipolytica和Megasphaera elsdenii。在解脂菌中，亚精胺与肽聚糖的α-羧基共价连接，而在其它菌株中，腐胺和尸胺与肽聚糖的相同基团连接。所有研究的厌氧菌含有连接到肽聚糖的多胺，迄今为止研究的没有磷酸甘油，心磷脂normurein脂蛋白在其包膜。这些微生物对钾离子载体莫能菌素具有抗性。

ABSTRACTPolyamine covalently linked to the cell wall peptidoglycan was found to occur in strictly anaerobic lactate fermenting bacteria. The strains included Selenomonas ruminantiom, S. sputigena, Veillonellaalcalescens, V parvula, Anaerovibrio lipolytica and Megasphaera elsdenii.In A. lipolytica, spermidine is linked covalently to the alpha-carboxylgroup of the peptidoglycan, while in other strains, putrescine and cadaverine are linked to the same group of the peptidoglycan. All the studied anaerobes containing polyamine linked to the peptidoglycan studied hitherto possessed neither phospatidylglvcerol, cardiolipin normurein lipoprotein in their envelopes. These microorganisms were resistant to monensin which is an ionophore for potassium iom.