A Study of Hemodynamics on Exercise Stress Test in Children of High Risk Group for Hypertension and High Risk Group for Arteriosolerosis
A Study of Hemodynamics on Exercise Stress Test in Children of High Risk Group for Hypertension and High Risk Group for Arteriosolerosis
批准号:
01570531
负责人:
HANEDA Noriyuki
金额:
$1.47万
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (C)
财政年份:
1989
资助国家:
日本
项目状态:
已结题
起止时间:
1989 至 1991
中文摘要
有据可查,在同龄儿童中,有一种跟踪现象,即从小血压高的儿童随着年龄的增长而血压升高,同样地,血压低的儿童最终也会血压低。血清总胆固醇也是如此,因此,在儿童食品中,高血压或高血清胆固醇水平,它们在未来转变为高血压或高胆固醇血症的可能性很高。在我们研究的早期,我们研究的早期指出,超声心动图测量被认为是这些放射性疾病的高危儿童的静息状态下的左室舒张功能下降。去年,对该组6-15岁的儿童进行了麦角仪负荷试验,并对与对照组同龄的正常儿童进行了负荷试验,并用超声心动图Wa…分析了运动负荷下的左室舒张功能S学得更多了。今年继续采用运动负荷试验对9~18岁儿童的左室舒张功能进行研究。对3名高血压男孩、3名血清胆固醇水平高的男孩和5名正常男孩进行运动负荷试验。超声心动图分析心功能。结果,与其他组相比,高血压组的心率和血压较早地增加。运动负荷下左心室收缩能力的增加是足够的,保留的容量保持得很好。也有通过运动负荷试验明确显示左室舒张功能下降的病例。从整体上看,今年和去年的病例加在一起,即使在静息状态下,也可以看到左室舒张功能的下降,包括校正的左心室等容松弛时间延长和左心室内径增加的峰值速度降低,运动负荷试验后这种下降更加明显。在运动负荷试验中,高血清胆固醇水平组的重复性往往高于高血压组。我们的研究结果表明,观察临床病程的重要性,并注意被认为是高血压或动脉硬化症高危组的儿童心功能的潜在下降。较少
英文摘要
It is well documented that there is the tracking phenomenon, that is, children showing high blood pressure among the children of the same age from childhood have high blood pressure with the advance of age and likewise those showing low blood pressure have low blood pressure eventually. The same goes for serum totalcholesterol Where, therefore, high blood pressure or high serum cholesterol levels in childfood, the probability is high that they shift to hypertension or hypercholesterolemia in the future.It was pointed out in the early year of our study that a decline in the left ventricular diastolic function at rest was shown by echocardiographic measurement about children considered at high risk of these adiilt diseases. Last year oercise stress test with an ergoineter was done for 6 to 15-year old children belonging to that group and done for normal children of the same age as the control, and the left ventricular diastolic function on exercise loading analyzed by echocardiography wa … More s studied. This year Lhe study oil the left veiitricular diastolic function by exercise stress test with 9 to 18-year old children was continued as in last year. Exercise loading with an ergometer was done for 3 I)oys with high blood pressure, 3 boys with high serum cholesterol levels and 5 normal boys as the control. And the cardiac function was analyzed by echocardiography. As a result, an increase in the heart rate and blood pressure was noted early in the high blood pressure group as compared with other groups. An increase in the contraction of the left ventricle against exercise loading was sufficient and the reserved capacity was kept well. There were cases in which a decline in the left ventricular diastolic function was made clear by exercise stress test. When viewed on the whole with the cases of this year and cases of last year put together, a decline in the left ventricular diastolic function including prolongation of the corrected left ventricular isovolumic relaxation time and a decrease of the peak velosity of increase in the left ventricular dimnsion was noted even at rest and became prominent with exercise stress test. The reproducibility tend to be higher with exercise stress test on the high serum cholesterol level group than on the high blood pressure group.The results of our study suggest the importance of observations on the clinical course with attention paid to the latent decline in the cardiac function in children considered belonging to a high risk group for hypertension or arteriosclerosis. Less
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Chuzo Mori, Noriyuki Haneda, Kenji Kishida, Yurika Harada, Shiro Seto, Koji Watanabe & Toshikazu Nishino.: "Tracking of blood pressure and cholesterol in children - The Shimane Heart Study -" Presented at Interdisciplinary Symposium on Gene,. Nutrition an
森忠三、羽田典之、岸田贤治、原田由里香、濑户四郎、渡边浩二
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Koji Watanabe: "Relation between blood pressure,left ventricular mass and pulsed doppler purameters in healthy school children" Acta Paeditrica Japonica. 32. 275-281 (1990)
Koji Watanabe:“健康学童血压、左心室质量和脉冲多普勒血流计之间的关系”Acta Paedtrica Japonica。
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Yurika Hayashi: "Changes of left ventricular isovolumic relaxation time with growth in children." Acta Paediatrica Japonica. 32. 282-290 (1990)
Yurika Hayashi:“左心室等容舒张时间随儿童生长的变化。”
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Yurika Harada, Chuzu Mori, Koji Watanabe, Kenji Kishida, Noriyuki Haneda, Hajime Iwatani, & Toshikazu Nishio: "Left ventricular diastolic function of children in high blood pressure tracking group" Acta Padiatr Jpn. 32. 530-539 (1990)
原田由里香、森中祖、渡边浩二、岸田贤治、羽田典之、岩谷肇、
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Yurika Harada: "Left ventricular diastolic function of children in high blood pressure tracking group." Acta Paediatrica Japonica. 32. 530-539 (1990)
Yurika Harada:“高血压追踪组儿童的左心室舒张功能。”
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共 15 条
Us-Japan collaborative cohort study on cardiovascular risk factor in childhood
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批准号:05670677
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.02万
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财政年份:1993
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负责人:HANEDA Noriyuki
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依托单位:
海外基金