Comparison of Photochemistry for various retinal-proteins : Consideration for relationship between their structure and function

(1)阐明了法老视紫红质（ppR）的光化学性质，并估算了其结合口袋的结构。(2)突变的视网膜蛋白质是从自然栖息的盐细菌和人工DNA中获得的，其特征为功能所必需的氨基酸提供了线索。(3)章鱼视紫红质的特点。(4)用红外光谱和拉曼光谱研究了细菌视紫红质、章鱼视紫红质的结构变化。(5)对鱿鱼视紫红质和细菌视紫红质的结晶进行了尝试，得到了一些有趣的结果。(6)首次发现光合作用对披衣菌的趋光性有干扰作用。阐明了类视紫红质蛋白及其感光机理。(7)发展了视黄醛异构化的分子动力学理论，分析了视黄醛的振动模式。

(1) Photochemistry of pharaonis phoborhodopsin (ppR) was made clear and the structure of binding pocket of retinal was estimated.(2) Mutant retinal proteins were obtained both from naturallyhabitant halobacteria and by artificial DNA.Characterization gave clues on amino acids essential for the function.(3) Octopus rhodopsin was well characterized.(4) Structural changes of bacteriorhodopsin, Octopus rhodopsin were investigated by FTIR and by Raman spectroscopy.(5) Crystallization of Squid rhodopsin and bacteriorhodopsin were tried and interesting findings were obtained.(6) Interference of phototaxis of Chlamydomonas by photosynthesis was first showed. Rhodopsin-like proteins and mechanism of photo-sensory were clarified.(7) Molecular dynamic theory of retinal isomerization and analysis of vibration mode of retinal were developed.