Biologically inert probes to unravel nutrient directed cellular processing

在这个项目中，我们将开发新的化合物，这些化合物可以作为细胞中存在的吸收营养物质和其他基本分子的途径的探测器，并展示如何产生新的试剂来识别和靶向特定的细胞群体。该项目将产生新的工具来理解生物过程，包括细胞的运输和处理。从这项工作中获得的见解有望帮助指导新试剂的开发，以选择性地将成像和生物活性试剂输送到细胞。

In this project we will develop novel compounds that can act as probes of the pathways present in cells for the uptake of nutrients and other essential molecules and show how to generate new agents for identifying and targeting specific populations of cells. The project will generate new tools for understanding biological processes including cell transport and processing. The insights gained from this work are expected to help guide the development of new agents for selectively delivering imaging and biologically active agents to cells.