Basic and clinical study of multifocal ERG

我们从多焦视网膜电信号(ERG)的记录方法、反应的来源以及在评估临床疾病中的有用性和局限性方面进行了研究。我们发现，一些视力差和中心暗点的患者在记录过程中可能表现出较差的固定能力，这可能会导致明显的伪影。在这种情况下，我们证明了在记录过程中，通过红外电视眼底摄像机进行眼底监测是必不可少的。与传统的黄斑ERG相比，多焦ERG中的a波被证明与传统的多焦ERG具有相同的起源。我们发现了一种新的临床实体-黄斑营养不良，其中眼底黄斑发现正常，只有多焦ERG显示出巨大的异常。我们将这种疾病称为“隐匿性黄斑营养不良症”。

We studied the multifocal electroretinogram (ERG) in terms of the recording methods, the origin of the response, and the usefulness and limitation in evaluating clinical diseases. We found that some patients with poor visual acuity and central scotoma may show poor fixation during recording, which may cause a significant artifact. In such case, we proved that the fundus monitor is essential through the infrared television fundus camera during recording.In comparison with the conventional focal macular ERG,the a-wave in multifocal ERG was proved to have the same origin to that of conventional multifocal ERG.We found a macular dystrophy with a new clinical entity where the ophthalmoscopical macular finding is normal and only the multifocal ERg shows enormous abnormality. We termed "Occult Macular Dystrophy" for this disorder.