EFFECT OF ECERCISE ON HUMAN DEFENCE MECHANISMS

我们研究了体育锻炼对人类防御机制的影响。首先综述了近年来体育锻炼后免疫参数变化的研究动向。我们发现运动会影响超氧化物的产生。我们研究了唾液中的免疫球蛋白A作为人类防御系统的指标的有用性。由于唾液是非侵入性获取的，因此它可能是评估体育领域人类防御系统的一种很好的工具。大强度训练营后，IgA水平下降，NK细胞活性也出现暂时性下降。检测运动后细胞因子的变化。白介素2受体和白介素6受体降低。细胞因子可能在应激改变免疫系统的机制中起重要作用。这项研究的这些结果可能表明，适当的运动可以增强人类的防御系统。

We investigated the effect of physical exercise on human defense mechanisms. Firstly we surveyed the recent research tendency focusing on the change of immune parameters after physical exercise. We found production of superoxide was influenced by exercise. We studied the usefulness of secretary IgA in saliva as, an indicator of human defense system. As saliva is obtained non-invasively, it might be a good tool to evaluate the human defense system in sports field. After intensive training camp, the IgA was elicited to decrease and NK cell activities was also found to decrease temporarily. We examined the change of cytokines after physical exercise. Interleukin 2 receptor and interleukin 6 receptor was found to decrease in plasma. Cytokines might play important role in the mechanisms of change of immune system by exersise stress. These results of this research might suggest that appropriate exercise enhance the human defense system.