Quantitative analysis of tin-hydrogenide-ICP-MS method

尽管如此。古人认识到锡是一种有害元素，可诱发尘肺、皮炎和中毒，最近的研究证明锡是动物生长发育所必需的微量元素之一。对锡造成的污染或缺乏进行评估的需求越来越大。然而，由于光谱干扰，用电感耦合等离子体发射质谱仪(ICPMS)测定样品中的锡含量时，由于光谱干扰，无法准确测定样品中锡的含量。为了解决这一问题，我们尝试建立了氢化物-电感耦合等离子体质谱分析方法。氢化法制备的氢化锡(SnH4)的相对分子质量为122，因此氢化物-液质联用法测定SnH4不受光谱干扰。该装置是将电感耦合等离子体质谱与市售的气液分离器连接起来。采用含1%盐酸的饱和波兰酸溶液作为载体。用此法测定SnH_4的最佳灵敏度为：1)以氩气为载气的流量为1.05~1.15 L/分钟，2)以硼烷为还原剂的浓度优于0.1%，3)以氢氧化钠为反应性碱性溶液的浓度为0.0596。该方法的准确度优于10ppt。该方法的重复性好于。使用该方法可以测量样品中锡的浓度，包括环境、动物组织和饮食中的锡。

Although. ancient people recognized that tin is a harmful element which induces pneumonoconiosis, dermatitis and intoxation, recent study proved tin is one of the essential trace elements contributed to animal growth. To evaluate the pollution or deficiency caused by tin is increasing in much demand. However, we cannot measure exactly the amount of tin in a specimen with inductively coupled plasma emission mass (ICP-MS) in the usual methods because of the spectrum interference. For removing this problem, we try to establish a hydrogenide- ICP-MS method analysis. Molecular weight of tin hydride (SnH4), made by hydrogenation, is 122, so SnH4 does not suffer from spectrum interference on measuring by hydrogenide- lCP-MS method. The equipment was made up to connect ICP-MS with gas-liquid separator on sale. We used saturated bolic acid solution with 1% HC1 as carrier solution. The best sensitivity on measuring SnH4 by this method was detected as follows : 1) flow volume of argon gas, as the carrier gas, was ranged 1.05-1.15 L/min, 2) concentration of sodium borane solution, as a reductant, was better than 0.1% and 3) concentration of sodium hydroxide, as a reactive alkaline solution, was 0.0596. The accuracy of this method was better than 10 ppt. Repeatability of this measurement was better than . For using this methods, we can measure the concentration of tin, which involved in specimen include in environment, animal tissue and diet.