A Method for Estimating Blood Flow by Velocity Profile Using Color Doppler Signals : Measurement of portal flow volume of children

传统的血流量估计是用脉冲多普勒法进行的。然而，这种方法是不准确的，因为通常很难确定精确的血管直径，并且因为使用从动物实验中获得的系数并不总是合适的。我们开发了一种方法，通过修改普通超声设备，使其能够用彩色多普勒信号测量血流的速度分布。1996年，我们用一个幻影来检验这种方法的有效性。所得结果与实际通过幻体的流量结果密切相关。我们还测量了狗股动脉的血容量。速度剖面法测量值与电磁法测量值具有较好的相关性。1997年，我们对100例正常儿童进行了门静脉血流形态的观察和门静脉流量的测量。门静脉血流模式随年龄和呼吸而改变，但体积不受呼吸和血流模式的影响。传统方法测量的门静脉流量不能反映门静脉直径的变化，而我们的新方法可以随时测量门静脉直径和流量，以反映任何流型下正确的流量。

Conventional estimation of blood flow volume has been done using pulsed Doppler method. This method is inaccurate, however, because it is often difficult to determine precise vessel diameter, and because it is not always appropriate to use the coefficient obtained from animal experiments. We developed a method for presenting a velocity profile of a blood flow by modifying an ordinary ultrasonographic apparatus to enable it to measure flow volume with color Doppler signals. In 1996 we used a phantom to examine the validity of the method. Results obtained correlated closely with those of the actual flow volume through the phantom. We also measured blood volume of femoral artery of a dog. Good correlation was found between the measurement values of the velocity profile method and electromagnetic one. In 1997 we observed the flow pattern of portal vein and measured portal flow volume in 100 normal children. Portal flow patterns changed with age and respiration, but volumes were not influenced by respiration or flow pattern. Portal flow volume measured by conventional method could not reflect the change of portal diameter, however, by our new method, portal diameter and flow volume were measured every moment to reflect the correct flow volume in any flow pattern.