Infection with New Type Hepatitis Viruses G and TTV, and Oral Malignant Tumors

对新型庚型肝炎病毒和输血传播病毒(TTV)以及乙型和丙型肝炎的感染与口腔疾病(包括口腔癌)的相关性进行了评估。口腔癌患者的丙型肝炎病毒抗体水平高于口腔囊肿者(8.6%比4.0%)，但这种差异随着年龄的调整而消失。另一方面，无论是否根据年龄进行调整，口腔囊肿患者中HBs抗原的发生率均高于口腔癌患者(2.1%vs.0%)。HGV RNA和TTV DNA在口腔癌和口腔囊肿组之间差异无统计学意义(HGV RNA 3.2%对2.8%，TTV DNA 29.7%对32.1%)。HBs抗原、丙型肝炎病毒抗体、HGV RNA和TTV DNA在阻生牙和颌骨畸形患者中的检测结果差异无统计学意义(HBs抗原1.1%比0%，丙型肝炎病毒抗体4.1%比3.2%，HGV RNA 1.8%比0%，TTV DNA 22.9%比21.4%)。总而言之，TTV DNA比其他病毒流行得多。未发现丙型肝炎病毒感染与口腔癌之间的病因学联系。

Prevalences of infection with new type hepatitis viruses G and transfusion transmitted virus (TTV) as well as with hepatitis B and C were evaluated in association with oral diseases including oral cancers. HCV antibody was more prevalent in patients with oral cancers than in those with oral cysts (8.6% vs. 4.0%), but this difference was disappeared with age adjustment. On the other hand, HBs antigen was more prevalent in patients with oral cysts than in those with oral cancers (2.1% vs. 0%), whether or not adjustment was made for age. No differences in HGV RNA or TTV DNA were found between oral cancers and oral cysts (3.2% vs. 2.8% for HGV RNA, 29.7% vs. 32.1% for TTV DNA ). There were no differences in HBs antigen, HCV antibody, HGV RNA, or TTV DNA between patients with impacted teeth and jaw deformities (1.1% vs. 0% for HBs antigen, 4.1% vs. 3.2% for HCV antibody, 1.8% vs. 0% for HGV RNA, 22.9% vs. 21.4% for TTV DNA). In conclusion, TTV DNA was much more prevalent than the other viruses. No etiological association was found between HCV infection and oral cancer.