Synthesis of graft copolymers based on chitin and chitosan via ring-opening graft copolymerization of lactide

合成了甲壳素、壳聚糖及其衍生物的接枝共聚物，作为环境友好的高分子材料。通过丙交酯与多糖的开环接枝共聚反应，制备了甲壳素接枝聚乳酸和壳聚糖接枝聚乳酸。然而，这些共聚物的摩尔取代度(MS)(定义为平均引入的乳酸单元数)非常低，以至于甲壳素和壳聚糖的物理性能没有得到改善。另一方面，成功合成了具有较高乳糖值的邻苯二甲酰化壳聚糖接枝聚乳酸。对于这种共聚物，证实了几个显著的物理性质的变化，如溶解度和热转变行为。

Graft copolymers based on chitin, chitosan and their derivatives were synthesized as environmentally conformable polymeric materials. Chitin-graft-poly(lactic acid) and chitosan- graft-poly(lactic acid) were obtained via ring-opening graft copolymerization of lactide onto polysaccharides. However, the molar substitution (MS) of these copolymers, defined as an average number of introduced lactil units, were so low that physical properties of chitin and chitosan were not improved. On the other hand, phthaloyl chitosan-graft-poly(lactic acid) having comparatively high value of lactyl MS was successfully synthesized. For this copolymer, several marked changes in physical properties, such as solubility and thermal transition behavior, were confirmed.