The research for repair of chronic spinal cord injury using autologas cells, growth factor and artificial extracellular matrix.

我们研制了大鼠脊髓损伤装置。使用这个装置，我们可以对脊髓造成固定的损伤。2周后，用免疫组织化学染色观察脊髓内固定大小的空洞。分别注射海藻酸凝胶和碱性成纤维细胞生长因子海藻酸凝胶。注射后，我们检查脊髓。我们证实抑制了腔的扩大和神经纤维的部分再生，但我们找不到统计学意义。

We made the device for making injury to spinal cords of rats. Using this device we could make fixed damage to spinal cords. After 2 weeks, we observe fixed size cavities in the spinal cords using immunohistochemical staining. We injected the alginate gel and the bFGF applied alginate gel. After injection, we investigate the spinal cord. We confirmed inhibition of enlargement of the cavities and partial regeneration of nerve fibers, but we could not find statistically significance.