Toward novel approaches for the control of parasitic nematodes via genomics/phenomics

对具有重要经济意义的牲畜寄生虫的控制在很大程度上依赖于化合物（驱虫药）的使用。它们的过度和不受控制的使用导致了寄生虫的严重抗虫问题，因此许多治疗方法不再有效，并且还导致了肉、牛奶和环境中的残留问题。我们将使用“尖端”技术，为寄生虫生长和繁殖的分子过程提供独特的见解，为寄生虫制定安全和可持续的干预策略。该项目将为寄生虫基因组学提供一个独特的技术平台和技能基础，并将产生重要的知识产权。

The control of economically important parasitic worms of livestock relies heavily on the use of chemical compounds (anthelmintics). Their excessive and uncontrolled use has led to serious anthelmintic resistance problems in parasites, so that many treatments are no longer effective, and also to residue problems in meat, milk and the environment. We will use 'cutting edge' technologies to provide unique insights into the molecular processes of parasite growth and reproduction, to develop safe and sustainable intervention strategies for parasites. The project will provide a unique technology platform and a skills base in parasite genomics and will generate significant intellectual property.