Study on growth, physiology and toxicology of Dinophysis spp. causing diarrheic shellfish poisoning

我们研究了牙藻属的生长、营养生理和亲脂毒素产生的特点以及环境条件对它们的影响。天然牙藻细胞毒素含量及毒素组成特征。澄清了在日本不同沿海水域收集的数据。在实验室实验中，牙藻的生长。依赖于特定的猎物来源，纤毛虫Myrionecta rubra以隐翅虫Teleaulax inioxeia为食，并受温度和光照强度的影响。毒素的产生也因环境因素和生长阶段的不同而不同。随着生长的进行，部分毒素组分排泄到周围海水中。在相同的培养条件下，不同品系间的细胞毒素含量偶尔会有很大差异，这表明遗传特性对毒素产生的影响。

We examined characteristics of growth, nutritional physiology and lipophilic toxin production of the genus Dinophysis and effects of environmental conditions on them. Characteristics of cellular toxin contents and toxin composition of natural Dinophysis spp. collected in various Japanese coastal waters were clarified. In laboratory experiments growth of Dinophysis spp. depends on specific prey source, the ciliate Myrionecta rubra, feeding on the Cryptophyceae Teleaulax amphioxeia, and was influenced by temperature and light intensity. Toxin production also varied in response to these environmental factors and growth phase. Parts of toxin components were excreted into surrounding seawater with progress of the growth. Cellular toxin contents were occasionally largely different among local strains of Dinophysis species cultivated under the same conditions, suggesting effects of genetic characteristics on the toxin production.