Analysis of regulatory mechanisms of odontoblast differentiationby novel gap junction protein
Analysis of regulatory mechanisms of odontoblast differentiationby novel gap junction protein
批准号:
20791583
负责人:
IWAMOTO Tsutomu
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009
中文摘要
为了寻找对牙齿发育有重要影响的基因,我们建立了牙齿cDNA文库,并一直在努力寻找新的功能基因。到目前为止,我们已经确定了一个新的基质蛋白基因,命名为TM14/Fibluin7。我们发现TM14/Fibluin 7在成牙细胞附着中起重要作用。此外,我们还发现了一个硬组织特异性的新型缝隙连接基因,并分析了它在牙齿、软骨和骨骼发育中的功能。
英文摘要
To find genes, important for tooth development, we had generated tooth cDNA library, and have been trying to find novel and functional genes. So far, we have identified a novel matrix protein gene, named TM14/Fibluin7. We found that TM14/Fibluin 7 has an important role for odontoblast attachment. And also, we have identified a hard tissue specific novel gap junction gene, and have been analyzing its function in tooth, cartilage and bone development.
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歯の形態形成におけるインテグリンと基底膜の相互作用
牙齿形态发生中整合素和基底膜之间的相互作用
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[福本敏、岩本勉, 他]
通讯作者:
他
DOI:
10.1016/j.archoralbio.2009.07.009
发表时间:
2009-10-01
期刊:
ARCHIVES OF ORAL BIOLOGY
影响因子:
3
作者:
[Iwamoto, Tsutomu, Yamada, Aya, Fukumoto, Satoshi]
通讯作者:
Fukumoto, Satoshi
細胞間結合を利用したエナメル芽細胞の分化制御法の開発
开发利用细胞间连接控制成釉细胞分化的方法
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[山田亜矢, 岩本 勉、福本恵美子, 野中和明, 福本 敏]
通讯作者:
福本 敏
Fibulins, multiple roles in matrix structures and functions
Fibulins,在矩阵结构和功能中的多种作用
DOI:
--
发表时间:
2009
期刊:
Cell Mol Life Sci (In press)
影响因子:
--
作者:
[S. de Vega, T. Iwamoto, et.al.]
通讯作者:
et.al.
Mechanisms of ameloblast differentiation by Neurotrophic Factors
神经营养因子诱导成釉细胞分化的机制
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Ono M, Iwamoto T, Yoshizaki K, Fukumoto S]
通讯作者:
Fukumoto S
共 18 条
Cell fate determination of mesenchymal stem cells by extracellular mechanical stress
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批准号:17H04414
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.98万
-
财政年份:2017
-
负责人:IWAMOTO Tsutomu
-
依托单位:
role of preodontoblast in tooth development
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批准号:26293435
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.57万
-
财政年份:2014
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负责人:IWAMOTO Tsutomu
-
依托单位:
Epithelial mesenchymal interaction mediated by exosomes in tooth development
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批准号:25670869
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
-
财政年份:2013
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负责人:IWAMOTO Tsutomu
-
依托单位:
Roles of gap junction proteins in odontoblast differentiation
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批准号:22689053
-
项目类别:Grant-in-Aid for Young Scientists (A)
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资助金额:$15.31万
-
财政年份:2010
-
负责人:IWAMOTO Tsutomu
-
依托单位:
Establishment of the dental pulp stem cell using a low molecular weight compound for tooth regeneration
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批准号:22659373
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项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.12万
-
财政年份:2010
-
负责人:IWAMOTO Tsutomu
-
依托单位:
海外基金