Experimental study on pain reduction mechanism of vertebroplasty for painful vertebral compression fracture

为了阐明经皮椎体成形术（骨水泥注射法）减轻疼痛的机制，我们进行了以下动物实验。对猪进行椎体压缩性骨折，并对压缩性骨折进行三种治疗。分别进行骨水泥注射、骨冲孔成形、钢丝固定，观察治疗效果的差异。从图像结果和猪的整体养殖情况来看，骨穿孔组仅达到与未处理组相当的效果。金属丝治疗与骨水泥治疗在第4天后达到了相当的水平，但最初的治疗效果很好。因此，事实证明用钢丝或骨水泥固定比椎体减压更有效。

In order to clarify the mechanism of the pain reduction of percutaneous vertebroplasty (Bone cement injection method) the animal experiments described below were performed. The vertebral compression fractures were made for the pigs, and three kinds of treatments were enforced to the compression fractures. That is, the cement injection, the bone punch formation, and the wire fixation were performed, and the difference of the therapeutic effect was observed. The bone punch formation group achieved only the effect equal with the treatment free group when judged from the result of obtaining from the image result and pig's breeding situation overall. Moreover, the metal wire treatment became equal to the bone cement treatment after the fourth day, though the initial therapeutic effect was excellent. Therefore, it turned out that the fixation with the wire or the bone cement more effective than the decompression of the vertebral body.