Health promotional effects of the combination of supplementation and exercise in old mice having various genetic backgrounds

本研究是一项基础医学研究，分析了营养供给与高强度间歇步行运动短期结合对不同遗传背景老年小鼠的健康促进作用。我们发现，小鼠的高空腹血糖水平在补充黄酮类化合物和运动干预后仅三周就得到改善，并且与单独运动相比，补充和运动相结合对肥胖有很好的效果。我们需要对营养素的剂量、介入时间、最佳途径和分子机制进行研究，但我们相信这些发现和策略对促进老年人的健康是有用的。

This study is a basic medical research that analyzed health promotional effects of the short-term combination of nutrient supply and high-intensity interval walking exercise in old mice having various genetic backgrounds. We found that high-levels of fasting blood glucose in mice were improved after the intervention of supplementation with flavonoids and exercise for only three weeks, and that the combination of supplementation and exercise had a good effect for obesity compared with exercise alone. We have to investigate a dose of nutrient, an interventional period, an optimal route, and the molecular mechanism, but we believe that these findings and strategies are useful to help the health promotion for the elderly person.