Specification and verification of periodontal pathogens relate to various vascular diseases
Specification and verification of periodontal pathogens relate to various vascular diseases
批准号:
21592621
负责人:
UMEDA Makoto
金额:
$2.66万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
制备了检测牙龈卟啉单胞菌和T.制备了组织标本中的局部组织。免疫组化法检测牙周病病原体在病变牙龈组织和动脉粥样硬化标本中的表达。采用聚合酶链反应方法对斯里兰卡Buerger病患者的口腔和血管标本进行牙周病原体检测。对有头颈部肿瘤病史的患者,用福尔马林固定石蜡包埋的口腔近端淋巴结进行牙周病原体检测。这些侵入牙龈组织的细菌可能通过淋巴结转移到外周动脉。
英文摘要
The monoclonal antibodies effective for the detection of P. gingivalis and T. forsythia localized in tissue specimens were prepared. Periodontal pathogen was detected in diseased gingival tissue and atherosclerosis sample by immunohistochemistry. Oral and vascular samples of Buerger disease patients in Sri Lanka were detected periodontal pathogens by polymerase chain reaction method. The existence of periodontal pathogens in formalin-fixed and paraffin embedded lymph nodes proximal to oral cavity was examined from patients with histories of head and neck cancer. These bacteria invaded in gingival tissues might translocate peripheral arteries via lymph nodes.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
新規に開発したモノクローナル抗体を用いた病的歯肉組織中の歯周病原細菌の検出と局在
使用新开发的单克隆抗体检测和定位病理牙龈组织中的牙周病原菌
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[RajakarunaG Amodini, 内田佳介, 梅田誠, 古川あすか, 和泉雄一, 江石義信]
通讯作者:
江石義信
ザ・ペリオドントロジー
牙周病学
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[Sato J, Nishimura M, Yamazaki M, Yoshida K, Kurashige Y, Saitoh M, Abiko Y., 青木 章,水谷幸嗣,和泉雄一(分担)]
通讯作者:
青木 章,水谷幸嗣,和泉雄一(分担)
Whole-blood platelet aggregation by Porphyromonas gingivalis in Patients with peripheral arterial disease
周围动脉疾病患者牙龈卟啉单胞菌引起的全血血小板聚集
DOI:
--
发表时间:
2011
期刊:
J Med and Dent Sci.
影响因子:
--
作者:
[Hiroyuki Notani, Yoshinori Inoue, Norihide Sugano, et al.]
通讯作者:
et al.
The periodontal anaerobe porphyromonas gingivalis induced platelet activation and increased aggregation in whole blood by rat model
牙周厌氧菌牙龈卟啉单胞菌通过大鼠模型诱导全血血小板活化和聚集增加
DOI:
--
发表时间:
2011
期刊:
Thromb Res
影响因子:
7.5
作者:
[Kangmin Y, Inoue Y, Umeda M, Terasaki H, Chen Z, Iwai T]
通讯作者:
Iwai T
DOI:
10.1111/j.1600-051x.2009.01467.x
发表时间:
2009-10-01
期刊:
JOURNAL OF CLINICAL PERIODONTOLOGY
影响因子:
6.7
作者:
[Chen, Yi-Wen, Nagasawa, Toshiyuki, Izumi, Yuichi]
通讯作者:
Izumi, Yuichi
共 11 条
Strategy Foundation of Preemptive medicine for peri-implantitis of patients with diabetes mellitus
-
批准号:17K11818
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
-
财政年份:2017
-
负责人:UMEDA Makoto
-
依托单位:
Study on Aquatic and Ecological Environment Formed by a Tropical Glacier and the runoff water and Impact Assessment from Climate Changes
-
批准号:24404015
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$6.41万
-
财政年份:2012
-
负责人:UMEDA Makoto
-
依托单位:
Study on factors and countermeasures of the water quality problem caused by internal algal load in reservoirs
-
批准号:21760380
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.83万
-
财政年份:2009
-
负责人:UMEDA Makoto
-
依托单位:
The colonization of periodontopathic bacteria in the oral cavity since childhood
-
批准号:11672080
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.37万
-
财政年份:1999
-
负责人:UMEDA Makoto
-
依托单位:
Changes of microbial flora from the subgingival pockets in the active phase of periodontitis.
-
批准号:07672069
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.47万
-
财政年份:1995
-
负责人:UMEDA Makoto
-
依托单位:
海外基金